Evidence map›Paper›PMID 34096182›Full record

ArticleThoracic cancer2021

The LungVision navigational platform for peripheral lung nodule biopsy and the added value of cryobiopsy.

Barak Pertzov, Evgeni Gershman, Shimon Izhakian, Moshe Heching, Shai Moshe Amor, Dror Rosengarten, Mordechai Reuven Kramer

Abstract read
In one paragraph

Article in Thoracic cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Observational
  2. Opportunities for Interventional Radiology in Transbronchial Interventions.Cardiovascular and interventional radiology · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. New developments in the imaging of lung cancer.Breathe (Sheffield, England) · 2024
    Review
  9. Review
  10. Robotic Bronchoscopy: Review of Three Systems.Life (Basel, Switzerland) · 2023
    Review
  11. Review
  12. Radial Endobronchial Ultrasound-guided Transbronchial CryobiopsyThe open respiratory medicine journal · 2023
    Article
  13. Advances in Diagnostic Bronchoscopy.Diagnostics (Basel, Switzerland) · 2021
    Review
  14. Article
  15. Artificial Intelligence in Interventional Pulmonology.Therapeutic advances in pulmonary and critical care medicine
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Barak PertzovPulmonary Division, Rabin Medical Center, Petach Tikva, Israel.ORCID 0000-0002-3077-3616
Evgeni GershmanPulmonary Division, Rabin Medical Center, Petach Tikva, Israel.
Shimon IzhakianPulmonary Division, Rabin Medical Center, Petach Tikva, Israel.
Moshe HechingPulmonary Division, Rabin Medical Center, Petach Tikva, Israel.
Shai Moshe AmorPulmonary Division, Rabin Medical Center, Petach Tikva, Israel.
Dror RosengartenPulmonary Division, Rabin Medical Center, Petach Tikva, Israel.
Mordechai Reuven KramerPulmonary Division, Rabin Medical Center, Petach Tikva, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe LungVision system is a novel augmented-fluoroscopy-based real-time navigation and guidance technology for bronchoscopy that can be integrated with any standard biopsy tool, including the cryoprobe, to enable real-time visualization and localization of pulmonary nodules.

objectivesTo evaluate the diagnostic yield and safety among patients undergoing peripheral pulmonary nodule biopsy with the LungVision system.

methodsThis prospective, single-center study was conducted at Rabin Medical Center in Israel. All patients that underwent peripheral pulmonary nodule biopsy with the LungVision system from January 2016 to August 2020 were included. All procedures were performed under moderate sedation. The primary outcome was tissue diagnosis by either identification of malignant cells or benign diagnosis. Secondary outcomes were safety and the added value of cryobiopsy.

resultsSixty-three procedures were performed during the study period. Median lesion size (interquartile range) was 25.0 mm (18-28 mm). The diagnostic yield overall was 27/33 (81.8%) and for lesions smaller than 20 mm was 13/18 (72.2%). In nine cases the transbronchial cryobiopsy showed tissue with malignant cells that were not found in any other biopsy material taken with other sampling tools. One patient was treated with a chest tube for a pneumothorax. No other major complications were reported.

conclusionsThe LungVision system showed good feasibility and safety for peripheral pulmonary nodule biopsy. The system is compatible with all biopsy tools, including the cryoprobe. Randomized controlled trials are needed to accurately ascertain its diagnostic yield.

Indexed as

AgedBronchoscopyFemaleFluoroscopyHumansImage-Guided BiopsyMaleMiddle AgedMultiple Pulmonary NodulesProspective StudiesSolitary Pulmonary Nodulebronchoscopycryobiopsydiagnostic yieldnavigationperipheral pulmonary nodule

Identifiers

PMID34096182
PMCPMC8258356

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.