Evidence map›Paper›PMID 34096051›Full record

ArticleBritish journal of haematology2021

Immune responses and therapeutic challenges in paediatric patients with new-onset acute myeloid leukaemia and concomitant COVID-19.

Pratik A Patel, Stacey A Lapp, Gabrielle Grubbs, Venkata V Edara, Christina A Rostad, Claire L Stokes, Melinda G Pauly, Evan J Anderson, Anne Piantadosi, Mehul S Suthar and 2 more

Abstract readCase ReportsLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in British journal of haematology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Pratik A PatelDepartment of Pediatrics, Division of Hematology/Oncology/Bone Marrow Transplantation, Emory University School of Medicine, Atlanta, GA, USA.ORCID 0000-0002-1689-6214
Stacey A LappDepartment of Pediatrics, Division of Infectious Diseases, Emory University School of Medicine, Atlanta, GA, USA.
Gabrielle GrubbsDivision of Viral Products, Center for Biologics Evaluation and Research, FDA, Silver Spring, MD, USA.
Venkata V EdaraDepartment of Pediatrics, Division of Infectious Diseases, Emory University School of Medicine, Atlanta, GA, USA.
Christina A RostadDepartment of Pediatrics, Division of Infectious Diseases, Emory University School of Medicine, Atlanta, GA, USA.
Claire L StokesDepartment of Pediatrics, Division of Hematology/Oncology/Bone Marrow Transplantation, Emory University School of Medicine, Atlanta, GA, USA.
Melinda G PaulyDepartment of Pediatrics, Division of Hematology/Oncology/Bone Marrow Transplantation, Emory University School of Medicine, Atlanta, GA, USA.
Evan J AndersonDepartment of Pediatrics, Division of Infectious Diseases, Emory University School of Medicine, Atlanta, GA, USA.
Anne PiantadosiDepartment of Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Mehul S SutharDepartment of Pediatrics, Division of Infectious Diseases, Emory University School of Medicine, Atlanta, GA, USA.
Surender KhuranaDivision of Viral Products, Center for Biologics Evaluation and Research, FDA, Silver Spring, MD, USA.
Himalee S SabnisDepartment of Pediatrics, Division of Hematology/Oncology/Bone Marrow Transplantation, Emory University School of Medicine, Atlanta, GA, USA.ORCID 0000-0002-3763-3253

Funding

Yerkes National Primate Research Center Role of type-I IFN in regulating COVID-19 induced inflammation and pathogenesisP51OD011132 · OD · EMORY UNIVERSITY · PI Joon Sup Lee · 2012 to 2026
$167.0M
Project-004U54CA260563 · NCI · EMORY UNIVERSITY · PI DHODAPKAR, MADHAV V, SANZ, IGNACIO E. · 2020 to 2024
$10.2M
Emory Executive Vice President for Health Affairs Synergy Fund awardEmory School of MedicineNational Institute of Allergy and Infectious Diseases (NIAID) 1U54CA260563-01National Institute of Allergy and Infectious Diseases (NIAID) P51OD011132National Institutes of Health (NIH)NCI NIH HHS U54 CA260563NIH HHS P51 OD011132Pediatric Research Alliance Center for Childhood Infections and Vaccines and Children's Healthcare of AtlantaVital Projects/Proteus fundsWoodruff Health Sciences Center 2020 COVID-19 CURE Award
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adenosine MonophosphateAdolescentAlanineAntimalarialsAntineoplastic AgentsAntiviral AgentsCOVID-19COVID-19 Drug TreatmentDisease ManagementHumansHydroxychloroquineHydroxyureaLeukemia, Myeloid, AcuteMaleSARS-CoV-2Young AdultAdenosine MonophosphateAlanineAntimalarialsAntineoplastic AgentsAntiviral AgentsHydroxychloroquineHydroxyurearemdesivirAMLchildrenCOVID-19induction chemotherapyserology

Identifiers

PMID34096051
PMCPMC8239563

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.