Evidence map›Paper›PMID 34096037›Full record

ArticleActa obstetricia et gynecologica Scandinavica2021

A prospective study comparing rectal water contrast-transvaginal ultrasonography with sonovaginography for the diagnosis of deep posterior endometriosis.

Fabio Barra, Umberto Leone Roberti Maggiore, Giulio Evangelisti, Carolina Scala, Franco Alessandri, Valerio Gaetano Vellone, Cesare Stabilini, Simone Ferrero

Registry-linked trialOpen access · hybridAbstract readComparative Study
In one paragraph

Article in Acta obstetricia et gynecologica Scandinavica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04296760 (Rectal Water-contrast Transvaginal Ultrasonography Versus Sonovaginography for the Diagnosis of Posterior Deep Pelvic Endometriosis), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04296760 completednot on this map

Rectal Water-contrast Transvaginal Ultrasonography Versus Sonovaginography for the Diagnosis of Posterior Deep Pelvic Endometriosis

TypeobservationalSponsorFabio BarraRan2018 to 2020Enrolled250ConditionsEndometriosis, Rectum, Endometriosis of Vagina, Endometriosis Rectovaginal Septum, Endometriosis PelvicArmsRectal water-contrast transvaginal ultrasonography, Sonovaginography
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Advances in Imaging for Assessing Pelvic Endometriosis.Diagnostics (Basel, Switzerland) · 2022
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Fabio BarraAcademic Unit of Obstetrics and Gynecology, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.ORCID https://orcid.org/0000-0003-4117-6603
Umberto Leone Roberti MaggioreGynecological Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy.ORCID https://orcid.org/0000-0002-3744-2668
Giulio EvangelistiAcademic Unit of Obstetrics and Gynecology, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.ORCID https://orcid.org/0000-0001-8075-7916
Carolina ScalaDivision of Obstetrics and Gynecology, Gaslini Institute, Genoa, Italy.ORCID https://orcid.org/0000-0001-7503-0034
Franco AlessandriUnit of Obstetrics and Gynecology, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Valerio Gaetano VelloneDepartment of Surgical and Diagnostic Sciences, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.ORCID https://orcid.org/0000-0002-5107-1584
Cesare StabiliniDepartment of Surgical and Diagnostic Sciences, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Simone FerreroAcademic Unit of Obstetrics and Gynecology, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.ORCID https://orcid.org/0000-0003-2225-5568
Ospedale Policlinico San Martino · ITUniversità degli Studi della Tuscia · ITFondazione IRCCS Istituto Nazionale dei Tumori · ITIstituto Giannina Gaslini · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPreoperative assessment of deep endometriotic (DE) nodules is necessary to inform patients about the possible treatments and provide informed consent in case of surgery. This study aims to investigate the diagnostic performance of rectal water-contrast transvaginal ultrasonography (RWC-TVS) and sonovaginography (SVG) in women with suspicion of posterior DE. MATERIAL AND

methodsThis prospective comparative study (NCT04296760) enrolled women with clinical suspicion of DE at our institution (Piazza della Vittoria 14 SRL, Genoa, Italy). Exclusion criteria were previous diagnosis of DE by imaging techniques or laparoscopy. All patients underwent RWC-TVS and SVG, independently performed by two gynecological sonologists blinded to the other technique's results. Patients underwent laparoscopic surgery within the following three months; imaging findings were compared with surgical and histological results.

resultsIn 208 of 281 (74.0%) patients included, posterior DE was surgically confirmed in rectosigmoid (n = 88), vagina (n = 21), rectovaginal septum (n = 34) and uterosacral ligaments (n = 156). RWC-TVS and SVG demonstrated similar sensitivity (SE; 93.8% vs 89.4%; p = 0.210) and specificity (SP; 86.3% vs 79.4%; p = 0.481) in diagnosing posterior DE. Specifically, both examinations had similar accuracy in detecting nodules of uterosacral ligaments (p = 0.779), vagina (p = 0.688) and rectovaginal septum (p = 0.824). RWC-TVS had higher SE (95.2% vs 82.0%; p = 0.003) and similar SP (99.5% vs 98.5%; p = 0.500) in diagnosing rectosigmoid endometriosis and estimated better infiltration of intestinal submucosa (p = 0.039), and distance between these nodules and anal verge (p < 0.001); only RWC-TVS allowed the estimation of bowel lumen stenosis. A similar proportion of discomfort was experienced during both examinations (p = 0.191), although a statistically higher mean visual analog score was reported during RWC-TVS (p < 0.001).

conclusionsAlthough RWC-TVS and SVG have similar accuracy in the diagnosis of DE, RWC-TVS performed better in assessment of the characteristics of rectosigmoid endometriosis.

Indexed as

AdultContrast MediaEndometriosisFemaleHumansProspective StudiesRectal DiseasesSensitivity and SpecificityUltrasonographyVaginaContrast Mediaenhanced transvaginal ultrasoundposterior compartment deep endometriosisrectal water contrast transvaginal ultrasonographyrectosigmoid endometriosissonovaginography

Identifiers

PMID34096037
PMCPMC8457128
OpenAlexW3169059422

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.