Evidence map›Paper›PMID 34095903›Full record

ArticleProceedings of the ... Symposium on Applied Computing. Symposium on Applied Computing2017

Ranking Novel Regulatory Genes in Gene Expression Profiles using NetExpress.

Belma Yelbay, Alexander Gow, Hasan M Jamil

Abstract read
In one paragraph

Article in Proceedings of the ... Symposium on Applied Computing. Symposium on Applied Computing, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Belma YelbayDepartment of Industrial Engineering, Sabanci University, Turkey.
Alexander GowCenter for Molecular Medicine and Genetics, Wayne State University, USA.
Hasan M JamilDepartment of Computer Science, University of Idaho, USA.

Funding

Trb3-Mediated Modulation of Oligodendrocyte StressR56NS067157 · NINDS · WAYNE STATE UNIVERSITY · PI GOW, ALEXANDER · 2011 to 2011
$380k
NINDS NIH HHS R56 NS067157
6 · The paper itself

Abstract

Understanding gene regulation by identifying gene products and determining their roles in regulatory networks is a complex process. A common computational method is to reverse engineer a regulatory network from gene expression profile, and sanitize the network using known information about the genes, their interactions and other properties to filter out unlikely interactors. Unfortunately, due to limited resources most gene expression studies have a limited and small number of time points, and most reverse engineering tools are unable to handle large numbers of genes. Both of these factors play significant roles in influencing the accuracy of the process. In this paper, we present a new gene ranking algorithm from gene expression profiles with a small number of time points so that the most relevant genes can be selected for reverse engineering. We also present a graphical interface called

Identifiers

PMID34095903
PMCPMC8173485

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.