ArticleAmerican heart journal plus : cardiology research and practice2021
Understanding the role of left and right ventricular strain assessment in patients hospitalized with COVID-19.
Article in American heart journal plus : cardiology research and practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Understanding the link between COVID-19, blood pressure and obesity: Perspectives from the New Orleans experience.American heart journal plus : cardiology research and practice · 2024Article
- Imaging for Cardiovascular Complications of COVID-19: Cardiac Manifestations in Context.The Canadian journal of cardiology · 2023Review
- Strain Echocardiography in Acute COVID-19 and Post-COVID Syndrome: More than Just a Snapshot.Biomedicines · 2023Review
- Echocardiography and Lung Ultrasound in Long COVID and Post-COVID Syndrome, a Review Document of the Austrian Society of Pneumology and the Austrian Society of Ultrasound in Medicine.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2023Review
- Oral ketone esters acutely improve myocardial contractility in post-hospitalized COVID-19 patients: A randomized placebo-controlled double-blind crossover study.Frontiers in nutrition · 2023Article
- Strain Echocardiographic Evaluation of Myocardial Involvement in Patients with Continuing Chest Pain after COVID-19 Infection.Arquivos brasileiros de cardiologia · 2023Article
- Right ventricular free wall longitudinal strain is independently associated with mortality in mechanically ventilated patients with COVID-19.Annals of intensive care · 2022Article
- Feasibility, Prediction and Association of Right Ventricular Free Wall Longitudinal Strain with 30-Day Mortality in Severe COVID-19 Pneumonia: A Prospective Study.Journal of clinical medicine · 2022Article
- Association between the Right Ventricular Longitudinal Shortening Fraction and Mortality in Acute Respiratory Distress Syndrome Related to COVID-19 Infection: A Prospective Study.Journal of clinical medicine · 2022Article
- Point of care echocardiography and lung ultrasound in critically ill patients with COVID-19.Wiener klinische Wochenschrift · 2021Article
- Echocardiography in Coronavirus Disease 2019 Era: A Single Tool for Diagnosis and Prognosis.Journal of cardiovascular echographyReview
- Two-dimensional Speckle-Tracking and Four-dimensional Echocardiographic Evaluation of Cardiac Involvement in Post-COVID-19 patients: Comparison of Symptomatic and Asymptomatic Groups.Journal of cardiovascular echographyArticle
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
backgroundCoronavirus disease 2019 (COVID-19) can cause cardiac injury resulting in abnormal right or left ventricular function (RV/LV) with worse outcomes. We hypothesized that two-dimensional (2D) speckle-tracking assessment of LV global longitudinal strain (GLS) and RV free wall strain (FWS) by transthoracic echocardiography can assist as markers for subclinical cardiac injury predicting increased mortality.
methodsWe performed 2D strain analysis via proprietary software in 48 patients hospitalized with COVID-19. Clinical information, demographics, comorbidities, and lab values were collected via retrospective chart review. The primary outcome was in-hospital mortality based on an optimized abnormal LV GLS value via ROC analysis and RV FWS.
resultsThe optimal LV GLS cutoff to predict death was -13.8%, with a sensitivity of 85% (95% CI 55-98%) and specificity of 54% (95% CI 36-71%). Abnormal LV GLS >-13.8% was associated with a higher risk of death [unadjusted hazard ratio 5.15 (95% CI 1.13-23.45),
conclusionAbnormal LV strain with a cutoff of >-13.8% in patients with COVID-19 is associated with significantly higher risk of death. Despite normal LVEF, abnormal LV GLS predicted worse outcomes in patients hospitalized with COVID-19. There was no mortality difference based on RV strain.
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