Evidence map›Paper›PMID 34095848›Full record

ArticleRSC medicinal chemistry2020

Investigation of thiazolyl-benzothiophenamides as potential agents for African sleeping sickness.

Ronald W Brown, Ashraf M Abdel-Megeed, Paul A Keller, Amy J Jones, Melissa L Sykes, Marcel Kaiser, Jonathan B Baell, Vicky M Avery, Christopher J T Hyland

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC medicinal chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 5 countries.

Ronald W BrownSchool of Chemistry and Molecular Bioscience, and Molecular Horizons Research Institute, University of Wollongong Wollongong 2522 NSW Australia chrhyl@uow.edu.au.ORCID https://orcid.org/0000-0001-6290-541X
Ashraf M Abdel-MegeedSchool of Chemistry and Molecular Bioscience, and Molecular Horizons Research Institute, University of Wollongong Wollongong 2522 NSW Australia chrhyl@uow.edu.au.
Paul A KellerSchool of Chemistry and Molecular Bioscience, and Molecular Horizons Research Institute, University of Wollongong Wollongong 2522 NSW Australia chrhyl@uow.edu.au.ORCID https://orcid.org/0000-0003-4868-845X
Amy J JonesDiscovery Biology, Griffith Institute for Drug Discovery, Griffith University Brisbane Innovation Park Nathan 4111 Australia.
Melissa L SykesDiscovery Biology, Griffith Institute for Drug Discovery, Griffith University Brisbane Innovation Park Nathan 4111 Australia.ORCID https://orcid.org/0000-0002-9379-9012
Marcel KaiserSwiss Tropical and Public Health Institute Basel 4051 Switzerland.
Jonathan B BaellMedicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University Parkville 3052 Australia.ORCID https://orcid.org/0000-0003-2114-8242
Vicky M AveryDiscovery Biology, Griffith Institute for Drug Discovery, Griffith University Brisbane Innovation Park Nathan 4111 Australia.ORCID https://orcid.org/0000-0003-4914-2299
Christopher J T HylandSchool of Chemistry and Molecular Bioscience, and Molecular Horizons Research Institute, University of Wollongong Wollongong 2522 NSW Australia chrhyl@uow.edu.au.ORCID https://orcid.org/0000-0002-9963-5924
University of Wollongong · AUGriffith University · AUAustralian Regenerative Medicine Institute · AUSwiss Tropical and Public Health Institute · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

African sleeping sickness is a potentially fatal neglected disease affecting sub-Saharan Africa. High-throughput screening identified the thiazolyl-benzothiophenamide

Identifiers

PMID34095848
PMCPMC8126881
OpenAlexW3088762944

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.