Evidence map›Paper›PMID 34095839›Full record

ReviewRSC medicinal chemistry2020

Functionalized gold nanoparticles: promising and efficient diagnostic and therapeutic tools for HIV/AIDS.

Shikha Gulati, Parinita Singh, Anchita Diwan, Ayush Mongia, Sanjay Kumar

Abstract readReview
In one paragraph

Review in RSC medicinal chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. RNA-Based Vaccines and Therapeutics Against Intracellular Pathogens.Methods in molecular biology (Clifton, N.J.) · 2024
    Review
  5. Review
  6. Article
  7. Pulmonary Delivery of Nonviral Nucleic Acid-Based Vaccines With Spotlight on Gold Nanoparticles.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shikha GulatiDepartment of Chemistry, Sri Venkateswara College, University of Delhi Delhi-110021 India shikha2gulati@gmail.com.ORCID https://orcid.org/0000-0002-1894-9842
Parinita SinghDepartment of Chemistry, Sri Venkateswara College, University of Delhi Delhi-110021 India shikha2gulati@gmail.com.
Anchita DiwanDepartment of Chemistry, Sri Venkateswara College, University of Delhi Delhi-110021 India shikha2gulati@gmail.com.
Ayush MongiaDepartment of Chemistry, Sri Venkateswara College, University of Delhi Delhi-110021 India shikha2gulati@gmail.com.
Sanjay KumarDepartment of Chemistry, Sri Venkateswara College, University of Delhi Delhi-110021 India shikha2gulati@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Functionalized gold nanoparticles are recognized as promising vehicles in the diagnosis and treatment of human immunodeficiency virus (HIV) owing to their excellent biocompatibility with biomolecules (like DNA or RNA), their potential for multivalency and their unique optical and structural properties. In this context, this review article focuses on the diverse detection abilities and delivery and uptake methodologies of HIV by targeting genes and proteins using gold nanoparticles on the basis of different shapes and sizes in order to promote its effective expression. In addition, recent trends in gold nanoparticle mediated HIV detection, delivery and uptake and treatment are highlighted considering their cytotoxic effects on healthy human cells.

Identifiers

PMID34095839
PMCPMC8126886

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.