ArticleBrain communications2021
Corpus callosum morphology in major mental disorders: a magnetic resonance imaging study.
Article in Brain communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- The Genetic Architecture of the Human Corpus Callosum and its Subregions.Nature communications · 2025Pooled it
- Brain-based Sex Differences in Depression: A Systematic Review of Neuroimaging Studies.Brain imaging and behavior · 2023Pooled it
- White matter abnormalities in paediatric obsessive-compulsive disorder: a systematic review of diffusion tensor imaging studies.Brain imaging and behavior · 2023Pooled it
- Deciphering white matter microstructural alterations in catatonia according to ICD-11: replication and machine learning analysis.Molecular psychiatry · 2025Article
- Brain Morphometry and Cognitive Features in the Prediction of Irritable Bowel Syndrome.Diagnostics (Basel, Switzerland) · 2025Article
- The corpus callosum in people with congenital adrenal hyperplasia (CAH).Scientific reports · 2025Article
- White matter correlates of dissociation in a diverse sample of trauma-exposed women.Psychiatry research · 2024Article
- How does the macroenvironment influence brain and behaviour-a review of current status and future perspectives.Molecular psychiatry · 2024Review
- Review
- Corpus callosum morphology and relationships to illness phenotypes in individuals with anorexia nervosa.Scientific reports · 2024Article
- Morphometric Analysis of Corpus Callosum in Individuals with Alzheimer's Disease: Magnetic Resonance Imaging (MRI) Study.Current Alzheimer research · 2024Article
- How does the macroenvironment influence brain and behaviour - a review of current status and future perspectives.medRxiv : the preprint server for health sciences · 2023Article
- Facial asymmetry in dogs with fear and aggressive behaviors towards humans.Scientific reports · 2022Article
- Topology of diffusion changes in corpus callosum in Alzheimer's disease: An exploratory case-control study.Frontiers in neurology · 2022Article
- Structural white matter alterations in borderline personality disorder: A narrative review and methodological considerations.Science progressReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mental disorders diagnosis is based on specific clinical criteria. However, clinical studies found similarities and overlapping phenomenology across a variety of disorders, which suggests a common neurobiological substrate. Thus, there is a need to measure disease-related neuroanatomical similarities and differences across conditions. While structural alterations of the corpus callosum have been investigated in obsessive-compulsive disorder, schizophrenia, major depressive disorder and bipolar disorder, no study has addressed callosal aberrations in all diseases in a single study. Moreover, results from pairwise comparisons (patients vs. controls) show some inconsistencies, possibly related to the parcellation methods to divide the corpus callosum into subregions. The main aim of the present paper was to uncover highly localized callosal characteristics for each condition (i.e. obsessive-compulsive disorder, schizophrenia, major depressive disorder and bipolar disorder) as compared either to healthy control subjects or to each other. For this purpose, we did not rely on any sub-callosal parcellation method, but applied a well-validated approach measuring callosal thickness at 100 equidistant locations along the whole midline of the corpus callosum. One hundred and twenty patients (30 in each disorder) as well as 30 controls were recruited for the study. All groups were closely matched for age and gender, and the analyses were performed controlling for the impact of antipsychotic treatment and illness duration. There was a significant main effect of group along the whole callosal surface. Pairwise
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