Evidence map›Paper›PMID 34095784›Full record

ArticleiScience2021

Hydra vulgaris shows stable responses to thermal stimulation despite large changes in the number of neurons.

Constantine N Tzouanas, Soonyoung Kim, Krishna N Badhiwala, Benjamin W Avants, Jacob T Robinson

Abstract read
In one paragraph

Article in iScience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Assembly of a functional neuronal circuit in embryos of an ancestral metazoan is influenced by temperature and the microbiome.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. A complete biomechanical model ofProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  10. Review
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Constantine N TzouanasDepartment of Bioengineering, Rice University, 6100 Main Street, Houston, TX 77005, USA.
Soonyoung KimDepartment of Electrical and Computer Engineering, Rice University, 6100 Main Street, Houston, TX 77005, USA.
Krishna N BadhiwalaDepartment of Bioengineering, Rice University, 6100 Main Street, Houston, TX 77005, USA.
Benjamin W AvantsDepartment of Electrical and Computer Engineering, Rice University, 6100 Main Street, Houston, TX 77005, USA.
Jacob T RobinsonDepartment of Bioengineering, Rice University, 6100 Main Street, Houston, TX 77005, USA.

Funding

Developing microfluidics and automated image analysis for high-throughput investigation of lifespan and health in a novel invertebrate model for agingR21AG067034 · NIA · MARINE BIOLOGICAL LABORATORY · PI GRIBBLE, KRISTIN, ROBINSON, JACOB T. · 2020 to 2021
$456k
NIA NIH HHS R21 AG067034
6 · The paper itself

Abstract

Many animals that lose neural tissue to injury or disease can maintain behavioral repertoires by regenerating new neurons or reorganizing existing neural circuits. However, most neuroscience small model organisms lack this high degree of neural plasticity. We show that

Indexed as

Behavioral neuroscienceBiological sciencesDevelopmental neuroscienceNeuroscience

Identifiers

PMID34095784
PMCPMC8164038

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.