ArticlePlant direct2021
Impact of nicotine pathway downregulation on polyamine biosynthesis and leaf ripening in tobacco.
Article in Plant direct, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 10 citations in OpenAlex.
- Metabolic engineering for tobacco quality improvement: Advances and perspectives.Metabolic engineering communications · 2026Review
- Proteomics analysis of nitrogen stress on the influence of carbon and nitrogen metabolism of flue-cured tobacco.BMC genomics · 2025Article
- Exploring Metabolic Characteristics in Different Geographical Locations and Yields ofMetabolites · 2024Article
- Subfunctionalization of Parental Polyamine Oxidase (PAO) Genes in the Allopolyploid TobaccoGenes · 2023Article
- Isolation of starch and protein degrading strainFrontiers in microbiology · 2023Article
- Topping and grafting affect the alkaloid content and gene expression patterns of tobacco (Plant direct · 2023Article
- Impact of nicotine pathway downregulation on polyamine biosynthesis and leaf ripening in tobacco.Plant direct · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Traditional breeding and molecular approaches have been used to develop tobacco varieties with reduced nicotine and secondary alkaloid levels. However, available low-alkaloid tobacco varieties have impaired leaf quality likely due to the metabolic consequences of nicotine biosynthesis downregulation. Recently, we found evidence that the unbalanced crosstalk between nicotine and polyamine pathways is involved in impaired leaf ripening of a low-alkaloid (LA) Burley 21 line having a mutation at the
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.