Evidence map›Paper›PMID 34095692›Full record

ArticleJournal of the Endocrine Society2021

Hirohito Shima, Etsuro Tokuhiro, Shingo Okamoto, Mariko Nagamori, Tsutomu Ogata, Satoshi Narumi, Akie Nakamura, Yoko Izumi, Tomoko Jinno, Erina Suzuki and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the Endocrine Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Frontiers in endocrinology · 2025
    Article
  4. Article
  5. Genetic Variability ofMolecular syndromology · 2024
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Hirohito ShimaDepartment of Molecular Endocrinology, National Research Institute for Child Health and Development, 157-8535 Tokyo, Japan.ORCID https://orcid.org/0000-0003-1172-7363
Etsuro TokuhiroDepartment of Pediatrics, Fujisawa City Hospital, 251-8550, Fujisawa, Japan.
Shingo OkamotoOkamoto Internal Medicine and Pediatrics Clinic, 633-0064, Sakurai, Japan.
Mariko NagamoriDepartment of Pediatrics, University of Toyama, 930-0194, Toyama, Japan.
Tsutomu OgataDepartment of Pediatrics, Hamamatsu University School of Medicine, 431-3192, Hamamatsu, Japan.
Satoshi NarumiDepartment of Molecular Endocrinology, National Research Institute for Child Health and Development, 157-8535 Tokyo, Japan.ORCID https://orcid.org/0000-0002-0940-4517
Akie NakamuraDepartment of Molecular Endocrinology, National Research Institute for Child Health and Development, 157-8535 Tokyo, Japan.
Yoko IzumiDepartment of Molecular Endocrinology, National Research Institute for Child Health and Development, 157-8535 Tokyo, Japan.
Tomoko JinnoDepartment of Molecular Endocrinology, National Research Institute for Child Health and Development, 157-8535 Tokyo, Japan.
Erina SuzukiDepartment of Molecular Endocrinology, National Research Institute for Child Health and Development, 157-8535 Tokyo, Japan.
Maki FukamiDepartment of Molecular Endocrinology, National Research Institute for Child Health and Development, 157-8535 Tokyo, Japan.ORCID https://orcid.org/0000-0001-9971-4035
National Center For Child Health and Development · JPAkebono Clinic · JPFujisawa City Hospital · JPHamamatsu University School of Medicine · JPUniversity of Toyama · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionKallmann syndrome (KS) is a genetically heterogeneous condition characterized by hypogonadotropic hypogonadism (HH) and olfactory dysfunction. Although PATIENTS AND

methodsA total of 117 patients with KS underwent mutation screening of

resultsSequence analysis identified 2 heterozygous variants of

conclusionThese results provide evidence that

Indexed as

gonadotropin deficiencyhypogonadotropic hypogonadismmutationpubertyWaardenburg syndrome

Identifiers

PMID34095692
PMCPMC8170842
OpenAlexW3150106589

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.