Evidence map›Paper›PMID 34095200›Full record

ReviewFrontiers in surgery2021

3D Printing in Breast Reconstruction: From Bench to Bed.

Xingdou Mu, Juliang Zhang, Yue Jiang

Registry-linked trialAbstract readReview
In one paragraph

Review in Frontiers in surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06993714 (A Prospective, Multicenter, Controlled Clinical Study of 3D-printed Biodegradable Breast Implants for Breast Restoration), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06993714 phase2recruitingnot on this mapstarted 2025, after this paper: background citation

A Prospective, Multicenter, Controlled Clinical Study of 3D-printed Biodegradable Breast Implants for Breast Restoration

TypeinterventionalSponsorXijing HospitalRan2025 to 2028Enrolled120ConditionsBreast Cancer, Breast ReconstructionArmsBreast restoration surgery based on 3D printed degradable biological implants, Traditional breast-conserving surgery, Traditional silicone prosthesis breast reconstruction
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. 3D bioprinting innovations: a new frontier in breast cancer research.Medical oncology (Northwood, London, England) · 2025
    Review
  3. Review
  4. Article
  5. Review
  6. Gland surgery · 2024
    Article
  7. Article
  8. Review
  9. [Update and Trends in Breast Reconstruction After Mastectomy].Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V... · 2023
    Article
  10. 3D-printed GelMA/CaSiORegenerative biomaterials · 2023
    Article
  11. Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xingdou MuDepartment of Breast and Thyroid Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Juliang ZhangDepartment of Breast and Thyroid Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Yue JiangDepartment of Breast and Thyroid Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Surgical management of breast cancer often results in the absence of the breast. However, existing breast reconstruction methods may not meet the need for a replacement tissue. Tissue engineering with the use of emerging materials offers the promise of generating appropriate replacements. Three-dimensional (3D) printing technology has seen a significantly increased interest and application in medically-related fields in the recent years. This has been especially true in complex medical situations particularly when abnormal or complicated anatomical surgical considerations or precise reconstructive procedures are contemplated. In addition, 3D bio-printing which combines cells with bio-material scaffolds offers an exciting technology with significant applications in the field of tissue engineering. The purpose of this manuscript was to review a number of studies in which 3D printing technology has been used in breast reconstructive surgical procedures, and future directions and applications of 3D bio-printing.

Indexed as

3D bio-printing3D printingbreast reconstructionfemale breast cancertissue engineering

Identifiers

PMID34095200
PMCPMC8173201

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.