ArticleFrontiers in chemistry2021
Modeling the Energy Landscape of Side Reactions in the Cytochrome bc
Article in Frontiers in chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 10 citations in OpenAlex.
- Unravelling Mechanisms of Oxinflammation Induced by Heavy Metals.Metabolites · 2026Review
- Weak Radiofrequency Field Effects on Biological Systems Mediated through the Radical Pair Mechanism.Chemical reviews · 2025Review
- Peculiar Differences between Two Copper Complexes Containing Similar Redox-Active Ligands: Density Functional and Multiconfigurational Calculations.Inorganic chemistry · 2024Article
- Cation-induced changes in the inner- and outer-sphere mechanisms of electrocatalytic CONature communications · 2023Article
- Long-Range Conductivity in Proteins Mediated by Aromatic Residues.ACS physical chemistry Au · 2023Article
- Long-Time Oxygen Localization in Electron Transfer Flavoprotein.Journal of chemical information and modeling · 2022Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Much of the metabolic molecular machinery responsible for energy transduction processes in living organisms revolves around a series of electron and proton transfer processes. The highly redox active enzymes can, however, also pose a risk of unwanted side reactions leading to reactive oxygen species, which are harmful to cells and are a factor in aging and age-related diseases. Using extensive quantum and classical computational modeling, we here show evidence of a particular superoxide production mechanism through stray reactions between molecular oxygen and a semiquinone reaction intermediate bound in the mitochondrial complex III of the electron transport chain, also known as the cytochrome
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