Evidence map›Paper›PMID 34094989›Full record

ArticleFrontiers in oncology2021

The Global, Regional, and National Burden and Trends of Breast Cancer From 1990 to 2019: Results From the Global Burden of Disease Study 2019.

Shangbo Xu, Yiyuan Liu, Taofeng Zhang, Jiehua Zheng, Weixun Lin, Jiehui Cai, Juan Zou, Yaokun Chen, Yanna Xie, Yexi Chen and 1 more

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In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shangbo XuDepartment of Internal Medicine, People's Hospital of Jieyang, Jieyang Hospital Affiliated to SunYat-sen University, Jieyang, China.
Yiyuan LiuDepartment of General Surgery, The Second Affiliated Hospital of Shantou University Medical College, Shantou, China.
Taofeng ZhangDepartment of General Surgery, The Second Affiliated Hospital of Shantou University Medical College, Shantou, China.
Jiehua ZhengDepartment of General Surgery, The Second Affiliated Hospital of Shantou University Medical College, Shantou, China.
Weixun LinDepartment of General Surgery, The Second Affiliated Hospital of Shantou University Medical College, Shantou, China.
Jiehui CaiDepartment of General Surgery, The Second Affiliated Hospital of Shantou University Medical College, Shantou, China.
Juan ZouDepartment of General Surgery, The Second Affiliated Hospital of Shantou University Medical College, Shantou, China.
Yaokun ChenDepartment of General Surgery, The Second Affiliated Hospital of Shantou University Medical College, Shantou, China.
Yanna XieDepartment of Internal Medicine, The First Affiliated Hospital of Shantou University Medical College, Shantou, China.
Yexi ChenDepartment of General Surgery, The Second Affiliated Hospital of Shantou University Medical College, Shantou, China.
Zhiyang LiDepartment of General Surgery, The Second Affiliated Hospital of Shantou University Medical College, Shantou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe burden of breast cancer has been increasing globally. The epidemiology burden and trends need to be updated. This study aimed to update the burden and trends of breast cancer incidences, deaths, and disability-adjusted life-years (DALYs) from 1990 to 2019, using the Global Burden of Disease 2019 study.

methodsThe data of incidences, deaths, DALYs, and age-standardized rates were extracted. Estimated annual percentage changes were used to quantify the trends of age-standardized rates. Besides, the population attributable fractions of the risk factors of breast cancer were also estimated.

resultsGlobally, the incidences of breast cancer increased to 2,002,354 in 2019. High social-development index (SDI) quintiles had the highest incidence cases with a declining trend in age-standardized incidence rate. In 2019, the global deaths and DALYs of breast cancer increased to 700,660 and 20,625,313, respectively. From 1990 to 2019, the age-standardized mortality rates and age-standardized DALY rates declined globally, especially in high and high-middle SDI quintiles. Besides, the trends varied from different regions and countries. The proportion of the patients in the 70+ years age group increased globally. Deaths of breast cancer attributable to high fasting plasma glucose and high body mass index increased globally, and high fasting plasma glucose was the greatest contributor to the global breast cancer deaths.

conclusionThe burden of breast cancer in higher SDI quintiles had gone down while the burden was still on the rise in lower SDI quintiles. It is necessary to appeal to the public to decrease the exposure of the risk factors.

Indexed as

breast cancerglobal cancer burdenincidencemortalityrisk factor

Identifiers

PMID34094989
PMCPMC8176863

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.