Evidence map›Paper›PMID 34094968›Full record

ReviewFrontiers in oncology2021

Frontiers in Bladder Cancer Genomic Research.

Yi Li, Lihui Sun, Xiangyang Guo, Na Mo, Jinku Zhang, Chong Li

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 1 country.

Yi LiDepartment of Anesthesiology, Peking University Third Hospital, Beijing, China.
Lihui SunCore Facility for Protein Research, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Xiangyang GuoDepartment of Anesthesiology, Peking University Third Hospital, Beijing, China.
Na MoDepartment of Pathology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, China.
Jinku ZhangDepartment of Pathology, First Central Hospital of Baoding, Baoding, China.
Chong LiCore Facility for Protein Research, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Baoding People's Hospital · CNBeijing Obstetrics and Gynecology Hospital · CNBeike Biotechnology (China) · CNInstitute of Biophysics · CNPeking University · CNPeking University Third Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Most of the etiology studies of bladder cancer focus on genetic changes, mainly including mutation and activation of oncogenes, mutation and inactivation of tumor suppressor genes, and rearrangement or heterozygous deletion of chromosomes. Moreover, bladder cancer is highly heterogeneous mainly due to abnormal changes in the genome and proteome of tumor cells. Surgery is the main treatment for bladder cancer, but because the recurrence rate is high after surgery and most of the muscle-invasive bladder cancer acquires distant metastasis. Therefore, there is a need to combine with chemotherapy to consolidate the treatment effect. However, there are differences in chemosensitivity among patients. In this article, we review the up-to-date genomic researches on bladder cancer occurrence, development, metastasis, and chemosensitivity in patients, in order to provide some theoretical support for the diagnosis and treatment strategy for bladder cancer.

Indexed as

bladder cancer genomicsepigeneticsheterogeneityoncogene sequencing methodprecision treatment

Identifiers

PMID34094968
PMCPMC8173177
OpenAlexW3162686004

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.