Evidence map›Paper›PMID 34094916›Full record

ArticleFrontiers in oncology2021

LncRNA HAS2-AS1 Promotes Glioblastoma Proliferation by Sponging miR-137.

Yalin Lu, Gaochao Guo, Rujun Hong, Xingjie Chen, Yan Sun, Fang Liu, Zhimeng Zhang, Xun Jin, Jun Dong, Kai Yu and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Yalin LuDepartment of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China.
Gaochao GuoDepartment of Neurosurgery, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou, China.
Rujun HongDepartment of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China.
Xingjie ChenDepartment of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China.
Yan SunDepartment of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China.
Fang LiuDepartment of Psychiatry and Imaging-Genetics and Co-morbidity (PNGC Lab), Tianjin Anding Hospital, Tianjin Mental Health Center, Mental Health Teaching Hospital, Tianjin Medical University, Tianjin, China.
Zhimeng ZhangDepartment of Neurosurgery, Ningbo Hospital of Zhejiang University, Ningbo, China.
Xun JinTianjin Medical University Cancer Institute and Hospital, Tianjin, China.
Jun DongDepartment of Neurosurgery, The Second Affiliated Hospital of Soochow University, Soochow, China.
Kai YuDepartment of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China.
Xuejun YangDepartment of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China.
Yang NanDepartment of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China.
Qiang HuangDepartment of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China.
Tianjin Medical University General Hospital · CNSecond Affiliated Hospital of Soochow University · CNTianjin Anding Hospital · CNTianjin Medical University Cancer Institute and Hospital · CNZhejiang University · CNZhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

GBM (Glioblastoma multiform) is the most malignant tumor type of the central nervous system and has poor diagnostic and clinical outcomes. LncRNAs (Long non-coding RNAs) have been reported to participate in multiple biological and pathological processes, but their underlying mechanism remains poorly understood. Here, we aimed to explore the role of the lncRNA HAS2-AS1 (HAS2 antisense RNA 1) in GBM. GSE103227 was analyzed, and qRT-PCR was performed to measure the expression of HAS2-AS1 in GBM. FISH (Fluorescence

Indexed as

ceRNAglioblastomalncRNALSD1miR-137

Identifiers

PMID34094916
PMCPMC8173206
OpenAlexW3160725319

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.