Evidence map›Paper›PMID 34094894›Full record

ArticleFrontiers in oncology2020

FUT8-AS1 Inhibits the Malignancy of Melanoma Through Promoting miR-145-5p Biogenesis and Suppressing NRAS/MAPK Signaling.

Xiang-Jun Chen, Sha Liu, Dong-Mei Han, De-Zhi Han, Wei-Jing Sun, Xiao-Chun Zhao, Jun-Qing Liang, Li Yu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. A multidimensional pan-cancer analysis of CD47 and its role in promoting malignant phenotype in pancreatic adenocarcinoma.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Article
  3. Review
  4. Immune surveillance interrupted: how cancer exploits trogocytosis.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  5. Clinical predictors of overall survival in pediatric patients with intramedullary spinal tumors: an analysis of the SEER database.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Xiang-Jun ChenDepartment of Burns and Plastic Surgery, The 969th Hospital of PLA, Hohhot, China.
Sha LiuDepartment of Burns and Plastic Surgery, The 969th Hospital of PLA, Hohhot, China.
Dong-Mei HanDepartment of Burns and Plastic Surgery, The 969th Hospital of PLA, Hohhot, China.
De-Zhi HanDepartment of Burns and Plastic Surgery, The 969th Hospital of PLA, Hohhot, China.
Wei-Jing SunDepartment of Burns and Plastic Surgery, The 969th Hospital of PLA, Hohhot, China.
Xiao-Chun ZhaoDepartment of Burns and Plastic Surgery, The 969th Hospital of PLA, Hohhot, China.
Jun-Qing LiangThe Affiliated People's Hospital of Inner Mongolia Medical University, Inner Mongolia Autonomous Region Cancer Hospital, Hohhot, China.
Li YuDepartment of Intensive Care Unit, The 969th Hospital of PLA, Hohhot, China.
Inner Mongolia Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Melanoma is the major lethal skin malignancy. However, the critical molecular drivers governing melanoma progression and prognosis are still not clear. By analyzing The Cancer Genome Atlas (TCGA) data, we identified FUT8-AS1 as a prognosis-related long non-coding RNA (lncRNA) in melanoma. We further confirmed that FUT8-AS1 is downregulated in melanoma. Reduced expression of FUT8-AS1 is correlated with aggressive clinical factors and inferior overall survival. Using

Indexed as

FUT8-AS1malignancyMAPK signalingmelanomamicroRNA biogenesisNF90

Identifiers

PMID34094894
PMCPMC8170315
OpenAlexW3163613469

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.