ArticleResults in physics2021
Controlling of pandemic COVID-19 using optimal control theory.
Article in Results in physics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 19 citations in OpenAlex.
- Cost-effectiveness analysis of COVID-19 intervention policies using a mathematical model: an optimal control approach.Scientific reports · 2024Article
- Interval type-2 Fuzzy control and stochastic modeling of COVID-19 spread based on vaccination and social distancing rates.Computer methods and programs in biomedicine · 2023Article
- Optimal Drug Regimen and Combined Drug Therapy and Its Efficacy in the Treatment of COVID-19: A Within-Host Modeling Study.Acta biotheoretica · 2022Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In 2019, a new infectious disease called pandemic COVID-19 began to spread from Wuhan, China. In spite of the efforts to stop the disease, being out of the control of the governments it spread rapidly all over the world. From then on, much research has been done in the world with the aim of controlling this contagious disease. A mathematical model for modeling the spread of COVID-19 and also controlling the spread of the disease has been presented in this paper. We find the disease-free equilibrium points as trivial equilibrium (TE), virus absenteeism equilibrium (VAE) and virus incidence equilibrium (VIE) for the proposed model; and at the trivial equilibrium point for the presented dynamic system we obtain the Jacobian matrix so as to be used in finding the largest eigenvalue. Radius spectral method has been used for finding the reproductive number. In the following, by adding a controller to the model and also using the theory of optimal control, we can improve the performance of the model. We must have a correct understanding of the system i.e. how it works, the various variables affecting the system, and the interaction of the variables on each other. To search for the optimal values, we need to use an appropriate optimization method. Given the limitations and needs of the problem, the aim of the optimization is to find the best solutions, to find conditions that result in the maximum of susceptiblity, the minimum of infection, and optimal quarantination.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.