Evidence map›Paper›PMID 34094656›Full record

ReviewAmerican journal of cancer research2021

Anti-ovarian cancer potential of phytocompound and extract from South African medicinal plants and their role in the development of chemotherapeutic agents.

Chella Perumal Palanisamy, Bo Cui, Hongxia Zhang, Mani Panagal, Sivagurunathan Paramasivam, Uma Chinnaiyan, Selvaraj Jeyaraman, Karthigeyan Murugesan, Mauricio Rostagno, Vijayakumar Sekar and 1 more

Abstract readReview
In one paragraph

Review in American journal of cancer research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Nanotheranostics for gynecological cancers: a path forward for Africa.Medical oncology (Northwood, London, England) · 2024
    Review
  2. Translational cancer research · 2024
    Article
  3. Review
  4. Combinatorial chemistry & high throughput screening · 2024
    Article
  5. Article
  6. Review
  7. Article
  8. 2-DimensionalFrontiers in bioengineering and biotechnology · 2022
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Chella Perumal PalanisamyState Key Laboratory of Biobased Material and Green Papermaking, College of Food Science and Engineering, Qilu University of Technology, Shandong Academy of Science Jinan 250353, China.
Bo CuiState Key Laboratory of Biobased Material and Green Papermaking, College of Food Science and Engineering, Qilu University of Technology, Shandong Academy of Science Jinan 250353, China.
Hongxia ZhangState Key Laboratory of Biobased Material and Green Papermaking, College of Food Science and Engineering, Qilu University of Technology, Shandong Academy of Science Jinan 250353, China.
Mani PanagalDepartment of Biotechnology, Annai College of Arts and Science Kovilacheri, Tamil Nadu, India.
Sivagurunathan ParamasivamDepartment of Microbiology, Faculty of Science, Annamalai University Tamil Nadu, India.
Uma ChinnaiyanDepartment of Microbiology, Faculty of Science, Annamalai University Tamil Nadu, India.
Selvaraj JeyaramanDepartment of Biochemistry, Saveetha University Chennai, Tamil Nadu, India.
Karthigeyan MurugesanDepartment of Biotechnology, Arumugam Pillai SeethaiAmmal College Tamil Nadu, India.
Mauricio RostagnoLaboratory of Functional Properties in Foods, School of Applied Sciences, University of Campinas Limeria, Sao Paulo, Brazil.
Vijayakumar SekarMarine College, Shandong University Weihai 264209, China.
Srinivasa Prabhu NatarajanDepartment of Biotechnology, Bharathidasan University Tamil Nadu, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ovarian cancer (OC) accounts for the highest tumor-related mortality among the gynecologic malignancies. Most of the OC patients diagnosed with advanced-stage (III and IV) this situation creates panic and provokes an emergency to discover a new therapeutic strategy. Plants that possess medicinal properties are gaining attention as they are enriched with various chemical compounds that are potential to treat various diseases. It is a prolonged process to provide innovative and significant leads against a range of pharmacological targets for a human disease management system. Though challenges and difficulties are faced in the development of a new drug, the emergence of combinatorial chemistry is providing a new ray of hope and also, the executed effort in discovering the drug, and a chemical compound has been remarkably successful. This review discussed the role of medicinal plants that are native of South Africa in treating the Ovarian Cancer and in drug discovery.

Indexed as

anti-ovarian cancer activitydrug developmentOvarian cancersouth african medicinal plants

Identifiers

PMID34094656
PMCPMC8167668

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.