Evidence map›Paper›PMID 34094517›Full record

ReviewClinical kidney journal2021

The renal patient seen by non-renal physicians: the kidney embedded in the 'milieu intérieur'.

Felix Perez-Villa, Marie Hélène Lafage-Proust, Eveline Gielen, Alberto Ortiz, Goce Spasovski, Àngel Argilés

Open access · goldAbstract readReview
In one paragraph

Review in Clinical kidney journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 3 countries.

Felix Perez-VillaServei de Cardiologia, Hospital Clínic, Barcelona, Spain.
Marie Hélène Lafage-ProustService de Rhumatologie-INSERM U 1059, CHU Saint-Etienne, Saint-Priest en Jarez, France.
Eveline GielenDepartment of Geriatrics and Centre for Metabolic Bone Diseases, Universitair Ziekenhuis Leuven, Leuven, Belgium.
Alberto OrtizDepartamento de Nefrologia e Hipertensión, Laura BaderInstituto de Investigación Sanitaria de la-Fundación Jimenez Diaz Universidad Autónoma de Madrid, Madrid, Spain.
Goce SpasovskiDepartment of Nephrology, University Hospital, Skopje, Macedonia.
Àngel ArgilésRD-Néphrologie, Montpellier, France.
Hospital Clínic de Barcelona · ESInserm · FRUniversidad Autónoma de Madrid · ESUniversitair Ziekenhuis Leuven · BEUniversité de Montpellier · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic kidney disease is defined as a decrease in renal function or evidence of kidney injury for >3 months. This represents an oversimplification that may confuse physicians. Thus kidney function is equated to glomerular filtration rate, which represents one of multiple kidney functions. Some potentially more important renal functions are lost earlier, such as the production for the anti-ageing factor Klotho. Overall, these changes modify the emergent properties of the body, altering the relationships between different organs and systems, in a manner that is difficult to predict the response to interventions based on normal physiology concepts, as there is a novel steady state of interorgan relations. In this regard we now discuss the impact of CKD on heart failure; osteomuscular and joint pain and bone fragility and fractures; and osteosarcopaenia as seen by a cardiologist, a rheumatologist and a geriatrician.

Indexed as

bone fragilitychronic kidney diseaseemergencefractureheart failurenetwork diseaseosteosarcopaenia

Identifiers

PMID34094517
PMCPMC8173597
OpenAlexW3144113502

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.