Evidence map›Paper›PMID 34094511›Full record

Trial reportJournal of nutritional science2021

A higher-protein nut-based snack product suppresses glycaemia and decreases glycaemic response to co-ingested carbohydrate in an overweight prediabetic Asian Chinese cohort: the Tū Ora postprandial RCT.

Louise W Lu, Marta P Silvestre, Ivana R Sequeira, Lindsay D Plank, Meika Foster, Nikki Middleditch, Alejandra Acevedo-Fani, Kieren G Hollingsworth, Sally D Poppitt

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of nutritional science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Louise W LuHuman Nutrition Unit, School of Biological Sciences, University of Auckland, Auckland, New Zealand.
Marta P SilvestreHuman Nutrition Unit, School of Biological Sciences, University of Auckland, Auckland, New Zealand.
Ivana R SequeiraHuman Nutrition Unit, School of Biological Sciences, University of Auckland, Auckland, New Zealand.
Lindsay D PlankDepartment of Surgery, University of Auckland, Auckland, New Zealand.
Meika FosterEdible Research Ltd, Christchurch, New Zealand.
Nikki MiddleditchHigh-Value Nutrition National Science Challenge, Auckland, New Zealand.
Alejandra Acevedo-FaniHigh-Value Nutrition National Science Challenge, Auckland, New Zealand.
Kieren G HollingsworthNewcastle Magnetic Resonance Centre, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK.
Sally D PoppittHuman Nutrition Unit, School of Biological Sciences, University of Auckland, Auckland, New Zealand.ORCID 0000-0002-2214-8378
University of Auckland · NZRiddet Institute · NZNewcastle University · GBUniversity of Otago · NZ

Funding

Medical Research Council G1100160
6 · The paper itself

Abstract

Nut-based products may aid low-glycaemic dietary strategies that are important for diabetes prevention in populations at increased risk of dysglycaemia, such as Asian Chinese. This randomised cross-over trial assessed the postprandial glycaemic response (0-120 min) of a higher-protein nut-based (HP-NB) snack formulation, in bar format (1009 kJ, Nutrient Profiling Score, NPS, -2), when compared with an iso-energetic higher-carbohydrate (CHO) cereal-based bar (HC-CB, 985 kJ, NPS +3). It also assessed the ability to suppress glucose response to a typical CHO-rich food (white bread, WB), when co-ingested. Ten overweight prediabetic Chinese adults (mean, sd: age 47⋅9, 15⋅7 years; BMI 25⋅5, 1⋅6 kg/m

Indexed as

Blood GlucoseNutsOverweightPrediabetic StateAdultChinaDietary CarbohydratesDietary ProteinsEdible GrainGlucoseGlycemic IndexHumansInsulinSnacksBlood GlucoseDietary CarbohydratesDietary ProteinsGlucoseInsulinAUC, area under the curveBF, body fatBMI, body mass indexCHO, carbohydrateDried fruitsDXA, dual-energy X-ray absorptiometryGI, glycaemic indexiAUC, incremental area under the curveMRIMRI, magnetic resonance imagingMRS, magnetic resonance spectroscopyNutsPostprandial glycaemiaPrediabetesSAT, subcutaneous adipose tissueT2D, type 2 diabetesVAS, visual analogue scalesVAT, visceral adipose tissueWB, white bread

Identifiers

PMID34094511
PMCPMC8141680
OpenAlexW3159765109

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.