Evidence map›Paper›PMID 34094453›Full record

ArticleChemical science2020

A metabolically engineered spin-labeling approach for studying glycans on cells.

Mohit Jaiswal, Trang T Tran, Qingjiang Li, Xin Yan, Mingwei Zhou, Krishnendu Kundu, Gail E Fanucci, Zhongwu Guo

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Mohit JaiswalDepartment of Chemistry, University of Florida 214 Leigh Hall Gainesville FL 32611 USA fanucci@chem.ufl.edu zguo@chem.ufl.edu.
Trang T TranDepartment of Chemistry, University of Florida 214 Leigh Hall Gainesville FL 32611 USA fanucci@chem.ufl.edu zguo@chem.ufl.edu.
Qingjiang LiDepartment of Chemistry, University of Florida 214 Leigh Hall Gainesville FL 32611 USA fanucci@chem.ufl.edu zguo@chem.ufl.edu.
Xin YanDepartment of Chemistry, University of Florida 214 Leigh Hall Gainesville FL 32611 USA fanucci@chem.ufl.edu zguo@chem.ufl.edu.
Mingwei ZhouDepartment of Chemistry, University of Florida 214 Leigh Hall Gainesville FL 32611 USA fanucci@chem.ufl.edu zguo@chem.ufl.edu.
Krishnendu KunduNational High Magnetic Field Laboratory, Florida State University Tallahassee Florida 32310 USA.
Gail E FanucciDepartment of Chemistry, University of Florida 214 Leigh Hall Gainesville FL 32611 USA fanucci@chem.ufl.edu zguo@chem.ufl.edu.ORCID https://orcid.org/0000-0003-1960-160X
Zhongwu GuoDepartment of Chemistry, University of Florida 214 Leigh Hall Gainesville FL 32611 USA fanucci@chem.ufl.edu zguo@chem.ufl.edu.ORCID https://orcid.org/0000-0001-5302-6456
University of Florida · USFlorida State University · US

Funding

Metabolic Engineering of Cancer for Selective Immunotargeting (NIH/NCI: 5R01CA095142-14)R01CA095142 · NCI · WAYNE STATE UNIVERSITY · PI GUO, ZHONGWU · 2002 to 2019
$3.3M
Synthetic and Biological Studies of GPI Conjugates and GPI Anchorage to Cell MembranesR35GM131686 · NIGMS · UNIVERSITY OF FLORIDA · PI Zhongwu Guo · 2019 to 2026
$2.5M
Acquisition of a Q Exactive HF Hybrid Quadrupole-OrbitrapS10OD021758 · OD · UNIVERSITY OF FLORIDA · PI BASSO, KARI B · 2017 to 2017
$600k
Upgrade to E500 X- and Q-Band CW EPR Spectrometer for Biomedical ResearchS10RR031603 · NCRR · UNIVERSITY OF FLORIDA · PI FANUCCI, GAIL E · 2011 to 2011
$523k
NCI NIH HHS R01 CA095142NCRR NIH HHS S10 RR031603NIGMS NIH HHS R35 GM131686NIH HHS S10 OD021758
6 · The paper itself

Abstract

Metabolic glycan engineering (MGE) coupled with nitroxide spin-labeling (SL) was utilized to investigate the heterogeneous environment of cell surface glycans in select cancer and normal cells. This approach exploited the incorporation of azides into cell surface glycans followed by a click reaction with a new nitroxide spin label. Both sialic acid and

Identifiers

PMID34094453
PMCPMC8162880
OpenAlexW3093607855

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.