Evidence map›Paper›PMID 34094445›Full record

ArticleChemical science2020

Preparation and characterization of the enol of acetamide: 1-aminoethenol, a high-energy prebiotic molecule.

Artur Mardyukov, Felix Keul, Peter R Schreiner

Abstract read
In one paragraph

Article in Chemical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. The enol of isobutyric acid.Chemical communications (Cambridge, England) · 2024
    Article
  2. CThe journal of physical chemistry. A · 2022
    Article
  3. 1,1,2-Ethenetriol: The Enol of Glycolic Acid, a High-Energy Prebiotic Molecule.Angewandte Chemie (International ed. in English) · 2021
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Artur MardyukovInstitute of Organic Chemistry, Justus Liebig University Heinrich-Buff-Ring 17 35392 Giessen Germany prs@uni-giessen.de.ORCID https://orcid.org/0000-0003-3908-6967
Felix KeulInstitute of Organic Chemistry, Justus Liebig University Heinrich-Buff-Ring 17 35392 Giessen Germany prs@uni-giessen.de.
Peter R SchreinerInstitute of Organic Chemistry, Justus Liebig University Heinrich-Buff-Ring 17 35392 Giessen Germany prs@uni-giessen.de.ORCID https://orcid.org/0000-0002-3608-5515

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amide tautomers, which constitute the higher-energy amide bond linkage, not only are key for a variety of biological but also prebiotic processes. In this work, we present the gas-phase synthesis of 1-aminoethenol, the higher-energy tautomer of acetamide, that has not been spectroscopically identified to date. The title compound was prepared by flash vacuum pyrolysis of malonamic acid and was characterized employing matrix isolation infrared as well as ultraviolet/visible spectroscopy. Coupled-cluster computations at the AE-CCSD(T)/cc-pVTZ level of theory support the spectroscopic assignments. Upon photolysis at

Identifiers

PMID34094445
PMCPMC8162875

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.