Evidence map›Paper›PMID 34094421›Full record

ArticleChemical science2020

LDL-mimetic lipid nanoparticles prepared by surface KAT ligation for

Alessandro Fracassi, Jianbo Cao, Naoko Yoshizawa-Sugata, Éva Tóth, Corey Archer, Olivier Gröninger, Emanuela Ricciotti, Soon Yew Tang, Stephan Handschin, Jean-Pascal Bourgeois and 7 more

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 4 countries.

Alessandro FracassiLaboratorium für Organische Chemie, ETH Zürich Vladimir-Prelog-Weg 3 CH-8093 Zürich Switzerland yamakoshi@org.chem.ethz.ch.ORCID https://orcid.org/0000-0003-1239-6527
Jianbo CaoDepartment of Radiology, Institute for Translational Medicine and Therapeutics, University of Pennsylvania John Morgan 198, 3620 Hamilton Walk Philadelphia PA19104 USA rongzhou@pennmedicine.upenn.edu.ORCID https://orcid.org/0000-0002-0859-1680
Naoko Yoshizawa-SugataDepartment of Genome Medicine, Tokyo Metropolitan Institute of Medical Science 2-1-6 Kamikitazawa, Setagaya Tokyo 156-8506 Japan.ORCID https://orcid.org/0000-0001-8792-8669
Éva TóthCentre de Biophysique Moléculaire, CNRS UPR 4301, Université dOrléans Rue Charles Sadron, 45071 Orléans Cedex 2 France.ORCID https://orcid.org/0000-0002-3200-6752
Corey ArcherInstitut für Geochemie und Petrologie, ETH Zürich Clausiusstrasse 25 CH-8092 Zürich Switzerland.ORCID https://orcid.org/0000-0002-6070-6297
Olivier GröningerInstitute for Chemical and Bioengineering, ETH Zurich Vladimir-Prelog-Weg 1 CH-8093 Zurich Switzerland.
Emanuela RicciottiDepartment of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania 3400 Civic Center Boulevard Philadelphia PA19104 USA.
Soon Yew TangDepartment of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania 3400 Civic Center Boulevard Philadelphia PA19104 USA.
Stephan HandschinScientific Center for Optical and Electron Microscopy, ETH Zürich Auguste-Piccard-Hof 1 Zürich CH-8093 Switzerland.
Jean-Pascal BourgeoisUniversity of Applied Science and Arts Western Switzerland Bd de Pérolles 80 CH-1700 Fribourg Switzerland.
Ankita RayLaboratorium für Organische Chemie, ETH Zürich Vladimir-Prelog-Weg 3 CH-8093 Zürich Switzerland yamakoshi@org.chem.ethz.ch.ORCID https://orcid.org/0000-0002-5059-9598
Korinne LiosiLaboratorium für Organische Chemie, ETH Zürich Vladimir-Prelog-Weg 3 CH-8093 Zürich Switzerland yamakoshi@org.chem.ethz.ch.ORCID https://orcid.org/0000-0001-5959-1683
Sean OrianaLaboratorium für Organische Chemie, ETH Zürich Vladimir-Prelog-Weg 3 CH-8093 Zürich Switzerland yamakoshi@org.chem.ethz.ch.
Wendelin StarkInstitute for Chemical and Bioengineering, ETH Zurich Vladimir-Prelog-Weg 1 CH-8093 Zurich Switzerland.ORCID https://orcid.org/0000-0003-3078-0354
Hisao MasaiDepartment of Genome Medicine, Tokyo Metropolitan Institute of Medical Science 2-1-6 Kamikitazawa, Setagaya Tokyo 156-8506 Japan.
Rong ZhouDepartment of Radiology, Institute for Translational Medicine and Therapeutics, University of Pennsylvania John Morgan 198, 3620 Hamilton Walk Philadelphia PA19104 USA rongzhou@pennmedicine.upenn.edu.ORCID https://orcid.org/0000-0003-4018-381X
Yoko YamakoshiLaboratorium für Organische Chemie, ETH Zürich Vladimir-Prelog-Weg 3 CH-8093 Zürich Switzerland yamakoshi@org.chem.ethz.ch.ORCID https://orcid.org/0000-0001-8466-0118
ETH Zurich · CHCalifornia University of Pennsylvania · USTokyo Metropolitan Institute of Medical Science · JPHES-SO University of Applied Sciences and Arts Western Switzerland · CHUniversité d'Orléans · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Low-density lipoprotein (LDL)-mimetic lipid nanoparticles (LNPs), decorated with MRI contrast agents and fluorescent dyes, were prepared by the covalent attachment of apolipoprotein-mimetic peptide (

Identifiers

PMID34094421
PMCPMC8162946
OpenAlexW3092396083

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.