Evidence map›Paper›PMID 34094417›Full record

ArticleChemical science2020

A copper-catalyzed asymmetric oxime propargylation enables the synthesis of the gliovirin tetrahydro-1,2-oxazine core.

Nicholas G W Cowper, Matthew J Hesse, Katie M Chan, Sarah E Reisman

Abstract read
In one paragraph

Article in Chemical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nicholas G W CowperThe Warren and Katharine Schlinger Laboratory of Chemistry and Chemical Engineering, California Institute of Technology Pasadena CA 91125 USA reisman@caltech.edu.ORCID https://orcid.org/0000-0003-4857-6052
Matthew J HesseThe Warren and Katharine Schlinger Laboratory of Chemistry and Chemical Engineering, California Institute of Technology Pasadena CA 91125 USA reisman@caltech.edu.ORCID https://orcid.org/0000-0002-4759-5086
Katie M ChanThe Warren and Katharine Schlinger Laboratory of Chemistry and Chemical Engineering, California Institute of Technology Pasadena CA 91125 USA reisman@caltech.edu.
Sarah E ReismanThe Warren and Katharine Schlinger Laboratory of Chemistry and Chemical Engineering, California Institute of Technology Pasadena CA 91125 USA reisman@caltech.edu.ORCID https://orcid.org/0000-0001-8244-9300

Funding

Chemical Synthesis of Chiral Bioactive MoleculesR35GM118191 · NIGMS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI Sarah Elizabeth Reisman · 2016 to 2026
$6.6M
NIGMS NIH HHS R35 GM118191
6 · The paper itself

Abstract

The bicyclic tetrahydro-1,2-oxazine subunit of gliovirin is synthesized through a diastereoselective copper-catalyzed cyclization of an

Identifiers

PMID34094417
PMCPMC8162951

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.