Evidence map›Paper›PMID 34094308›Full record

ArticleChemical science2020

Copper-mediated peptide arylation selective for the N-terminus.

Mary K Miller, Haopei Wang, Kengo Hanaya, Olivia Zhang, Alex Berlaga, Zachary T Ball

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Review
  3. Recent Advances in Bioorthogonal Ligation and Bioconjugation.Topics in current chemistry (Cham) · 2023
    Review
  4. Review
  5. Article
  6. Selective Stepwise Arylation of Unprotected Peptides by PtAngewandte Chemie (International ed. in English) · 2022
    Article
  7. Merging the Versatile Functionalities of Boronic Acid with Peptides.International journal of molecular sciences · 2021
    Review
  8. Article
  9. Article
  10. Gold-Based Pharmacophore Inhibits Intracellular MYC Protein.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Mary K MillerDepartment of Chemistry, Rice University Houston TX 77005 USA zb1@rice.edu.ORCID https://orcid.org/0000-0003-2507-907X
Haopei WangDepartment of Chemistry, Rice University Houston TX 77005 USA zb1@rice.edu.ORCID https://orcid.org/0000-0001-9756-8783
Kengo HanayaDepartment of Chemistry, Rice University Houston TX 77005 USA zb1@rice.edu.ORCID https://orcid.org/0000-0002-9152-5966
Olivia ZhangDepartment of Chemistry, Rice University Houston TX 77005 USA zb1@rice.edu.ORCID https://orcid.org/0000-0002-4299-1485
Alex BerlagaDepartment of Chemistry, Rice University Houston TX 77005 USA zb1@rice.edu.ORCID https://orcid.org/0000-0001-6326-1695
Zachary T BallDepartment of Chemistry, Rice University Houston TX 77005 USA zb1@rice.edu.ORCID https://orcid.org/0000-0002-8681-0789
Rice University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polypeptides present remarkable selectivity challenges for chemical methods. Amino groups are ubiquitous in polypeptide structure, yet few paradigms exist for reactivity and selectivity in arylation of amine groups. This communication describes the utilization of boronic acid reagents bearing certain

Identifiers

PMID34094308
PMCPMC8162437
OpenAlexW3085395657

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.