Evidence map›Paper›PMID 34094292›Full record

ArticleChemical science2020

A NIR-I light-responsive superoxide radical generator with cancer cell membrane targeting ability for enhanced imaging-guided photodynamic therapy.

Yingcui Bu, Tianren Xu, Xiaojiao Zhu, Jie Zhang, Lianke Wang, Zhipeng Yu, Jianhua Yu, Aidong Wang, Yupeng Tian, Hongping Zhou and 1 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 107 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Yingcui BuCollege of Chemistry and Chemical Engineering, Institute of Physical Science and Information Technology, Key Laboratory of Functional Inorganic Materials Chemistry of Anhui Province, Anhui Province Key Laboratory of Chemistry for Inorganic/Organic Hybrid Functionalized Materials, Key Laboratory of Structure and Functional Regulation of Hybrid Materials, Anhui University, Ministry of Education Hefei 230601 P. R. China xiaojzhu@ahu.edu.cn zhpzhp@263.net.
Tianren XuCollege of Chemistry and Chemical Engineering, Institute of Physical Science and Information Technology, Key Laboratory of Functional Inorganic Materials Chemistry of Anhui Province, Anhui Province Key Laboratory of Chemistry for Inorganic/Organic Hybrid Functionalized Materials, Key Laboratory of Structure and Functional Regulation of Hybrid Materials, Anhui University, Ministry of Education Hefei 230601 P. R. China xiaojzhu@ahu.edu.cn zhpzhp@263.net.
Xiaojiao ZhuCollege of Chemistry and Chemical Engineering, Institute of Physical Science and Information Technology, Key Laboratory of Functional Inorganic Materials Chemistry of Anhui Province, Anhui Province Key Laboratory of Chemistry for Inorganic/Organic Hybrid Functionalized Materials, Key Laboratory of Structure and Functional Regulation of Hybrid Materials, Anhui University, Ministry of Education Hefei 230601 P. R. China xiaojzhu@ahu.edu.cn zhpzhp@263.net.
Jie ZhangInstitute of Physical Science and Information Technology, Anhui University Hefei 230601 P. R. China.
Lianke WangInstitute of Physical Science and Information Technology, Anhui University Hefei 230601 P. R. China.ORCID https://orcid.org/0000-0002-5011-7552
Zhipeng YuInstitute of Physical Science and Information Technology, Anhui University Hefei 230601 P. R. China.
Jianhua YuCollege of Chemistry and Chemical Engineering, Institute of Physical Science and Information Technology, Key Laboratory of Functional Inorganic Materials Chemistry of Anhui Province, Anhui Province Key Laboratory of Chemistry for Inorganic/Organic Hybrid Functionalized Materials, Key Laboratory of Structure and Functional Regulation of Hybrid Materials, Anhui University, Ministry of Education Hefei 230601 P. R. China xiaojzhu@ahu.edu.cn zhpzhp@263.net.
Aidong WangHuangshan University Huangshan 242700 P. R. China.
Yupeng TianCollege of Chemistry and Chemical Engineering, Institute of Physical Science and Information Technology, Key Laboratory of Functional Inorganic Materials Chemistry of Anhui Province, Anhui Province Key Laboratory of Chemistry for Inorganic/Organic Hybrid Functionalized Materials, Key Laboratory of Structure and Functional Regulation of Hybrid Materials, Anhui University, Ministry of Education Hefei 230601 P. R. China xiaojzhu@ahu.edu.cn zhpzhp@263.net.ORCID https://orcid.org/0000-0003-2811-2066
Hongping ZhouCollege of Chemistry and Chemical Engineering, Institute of Physical Science and Information Technology, Key Laboratory of Functional Inorganic Materials Chemistry of Anhui Province, Anhui Province Key Laboratory of Chemistry for Inorganic/Organic Hybrid Functionalized Materials, Key Laboratory of Structure and Functional Regulation of Hybrid Materials, Anhui University, Ministry of Education Hefei 230601 P. R. China xiaojzhu@ahu.edu.cn zhpzhp@263.net.ORCID https://orcid.org/0000-0001-9583-2595
Yi XieHefei National Laboratory for Physical Sciences at Microscale, iChem, University of Science and Technology of China Hefei P. R. China.ORCID https://orcid.org/0000-0002-1416-5557
Anhui University · CNHuangshan University · CNUniversity of Science and Technology of China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photodynamic therapy (PDT), as an emerging treatment modality, which takes advantage of reactive oxygen species (ROS) generated upon light illumination to ablate tumours, has suffered from a limited treatment depth, strong oxygen dependence and short ROS lifespan. Herein, we developed a highly efficient NIR-I light (808 nm laser) initiated theranostic system based on a fluorescent photosensitizer (EBD-1) with cancer cell membrane targeting ability, which can realize large penetration depth in tissue, generate superoxide radicals (O

Identifiers

PMID34094292
PMCPMC8162420
OpenAlexW3083255042

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.