ArticleChemical science2020
3-Aminooxetanes: versatile 1,3-amphoteric molecules for intermolecular annulation reactions.
Article in Chemical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Synthesis of γ‑Lactams by Intermolecular (3 + 2) Annulation of Siloxy Alkynes and 3‑Aminooxetanes.Precision chemistry · 2025Article
- Recent Advances in Enantioselective Desymmetrizations of Prochiral Oxetanes.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021Review
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Authors and funding
4 authors.
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Abstract
Despite the versatility of amphoteric molecules, stable and easily accessible ones are still limitedly known. As a result, the discovery of new amphoteric reactivity remains highly desirable. Herein we introduce 3-aminooxetanes as a new family of stable and readily available 1,3-amphoteric molecules and systematically demonstrated their amphoteric reactivity toward polarized π-systems in a diverse range of intermolecular [3 + 2] annulations. These reactions not only enrich the reactivity of oxetanes, but also provide convergent access to valuable heterocycles.
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