Evidence map›Paper›PMID 34094247›Full record

ArticleChemical science2020

Self-assembled amphiphilic fluorescent probe: detecting pH-fluctuations within cancer cells and tumour tissues.

Soo Yeon Kim, Arup Podder, Hyunseung Lee, Youn-Joo Cho, Eun Hee Han, Sabina Khatun, Jonathan L Sessler, Kwan Soo Hong, Sankarprasad Bhuniya

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Ratiometric, pH-Sensitive Probe for Monitoring siRNA Delivery.Journal of the American Chemical Society · 2023
    Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 4 countries.

Soo Yeon KimResearch Center for Bioconvergence Analysis, Korea Basic Science Institute Cheongju 28119 Korea kshong@kbsi.re.kr.
Arup PodderAmrita Centre for Industrial Research & Innovation, Amrita Vishwa Vidyapeetham Ettimadai Coimbatore 641-112 India b_sankarprasad@cb.amrita.edu.
Hyunseung LeeResearch Center for Bioconvergence Analysis, Korea Basic Science Institute Cheongju 28119 Korea kshong@kbsi.re.kr.
Youn-Joo ChoResearch Center for Bioconvergence Analysis, Korea Basic Science Institute Cheongju 28119 Korea kshong@kbsi.re.kr.
Eun Hee HanResearch Center for Bioconvergence Analysis, Korea Basic Science Institute Cheongju 28119 Korea kshong@kbsi.re.kr.
Sabina KhatunAmrita Centre for Industrial Research & Innovation, Amrita Vishwa Vidyapeetham Ettimadai Coimbatore 641-112 India b_sankarprasad@cb.amrita.edu.
Jonathan L SesslerDepartment of Chemistry, The University of Texas at Austin Austin Texas 78712-1224 USA sessler@cm.utexas.edu.ORCID https://orcid.org/0000-0002-9576-1325
Kwan Soo HongResearch Center for Bioconvergence Analysis, Korea Basic Science Institute Cheongju 28119 Korea kshong@kbsi.re.kr.ORCID https://orcid.org/0000-0003-4342-5183
Sankarprasad BhuniyaAmrita Centre for Industrial Research & Innovation, Amrita Vishwa Vidyapeetham Ettimadai Coimbatore 641-112 India b_sankarprasad@cb.amrita.edu.ORCID https://orcid.org/0000-0001-5080-0936
Biocon (Switzerland) · CHOrthopaedic Research Group · INThe University of Texas at Austin · US

Funding

Biomedical Applications of Expanded Porphyrins: Development of Gold-Texaphyrin ConjugatesR01CA068682 · NCI · UNIVERSITY OF TEXAS AUSTIN · PI Esther Y. Maier, Emily L Que · 1995 to 2026
$7.4M
NCI NIH HHS R01 CA068682
6 · The paper itself

Abstract

Abnormal anaerobic metabolism leads to a lowering of the pH of many tumours, both within specific intracellular organelles and in the surrounding extracellular regions. Information relating to pH-fluctuations in cells and tissues could aid in the identification of neoplastic lesions and in understanding the determinants of carcinogenesis. Here we report an amphiphilic fluorescent pH probe (

Identifiers

PMID34094247
PMCPMC8162098
OpenAlexW3081945937

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.