ArticleChemical science2020
Nickel-catalyzed three-component olefin reductive dicarbofunctionalization to access alkylborates.
Article in Chemical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 84 citations in OpenAlex.
- Catalytic Reductive Annulation Reactions of Alkenes Using Dihaloalkanes.Tetrahedron letters · 2025Article
- Iron-catalysed radical difunctionalization of alkenes.Nature synthesis · 2025Article
- Triple cross-electrophile coupling enabled by palladium/norbornene cooperative catalysis.Science advances · 2025Article
- 2,6-Bis(pyrazol-1-yl)pyridine (1-bpp) as a General Ligand for the Negishi Alkylation of Alkylpyridinium Salts.The Journal of organic chemistry · 2024Article
- Nickel-Catalyzed Three-Component 1,2-Carboacylation of Alkenes.Molecules (Basel, Switzerland) · 2024Article
- Regio- and Enantioselective Hydromethylation of 3-Pyrrolines and Glycals Enabled by Cobalt Catalysis.JACS Au · 2024Article
- CoH-catalyzed asymmetric remote hydroalkylation of heterocyclic alkenes: a rapid approach to chiral five-membered S- and O-heterocycles.Chemical science · 2024Article
- Congested C(sp3)-rich architectures enabled by iron-catalysed conjunctive alkylation.Nature catalysis · 2024Article
- Three-Component Cross-Electrophile Coupling: Regioselective Electrochemical Dialkylation of Alkenes.Journal of the American Chemical Society · 2023Article
- Nickel-Catalyzed Regioselective Intermolecular Dialkylation of Alkenylarenes: Generation of Two Vicinal C(spAngewandte Chemie (International ed. in English) · 2023Article
- Dual Nickel/Photoredox-Catalyzed Asymmetric Carbosulfonylation of Alkenes.Journal of the American Chemical Society · 2023Article
- Three-component reductive conjugate addition/aldol tandem reaction enabled by nickel/photoredox dual catalysis.Chemical science · 2023Article
- Synthesis of Vicinal Carbocycles by Intramolecular Nickel-Catalyzed Conjunctive Cross-Electrophile Coupling Reaction.Organic letters · 2022Article
- Three-component carboacylation of alkenesChemical science · 2022Article
- Ni-Catalyzed Regio- and Stereoselective Alkylarylation of Unactivated Alkenes in γ,δ-Alkenylketimines.ACS catalysis · 2022Article
- Rapid access toChemical science · 2022Article
- Fe-Catalyzed dicarbofunctionalization of electron-rich alkenes with Grignard reagents and (fluoro)alkyl halides.Chemical communications (Cambridge, England) · 2021Article
- General method for iron-catalyzed multicomponent radical cascades-cross-couplings.Science (New York, N.Y.) · 2021Article
- Catalytic asymmetric reductive hydroalkylation of enamides and enecarbamates to chiral aliphatic amines.Nature communications · 2021Article
- Metal-free visible-light-enabled vicinal trifluoromethyl dithiolation of unactivated alkenes.Beilstein journal of organic chemistry · 2021Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We report a three-component olefin reductive dicarbofunctionalization for constructing alkylborates, specifically, nickel-catalyzed reductive dialkylation and alkylarylation of vinyl boronates with a variety of alkyl bromides and aryl iodides. This reaction exhibits good coupling efficiency and excellent functional group compatibility, providing convenient access to the late-stage modification of complex natural products and drug molecules. Combined with alkylborate transformations, this reaction could also find applications in the modular and convergent synthesis of complex compounds.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.