Evidence map›Paper›PMID 34094137›Full record

ArticleChemical science2020

Synthesis of secondary and tertiary amides without coupling agents from amines and potassium acyltrifluoroborates (KATs).

Anne Schuhmacher, Tomoya Shiro, Sarah J Ryan, Jeffrey W Bode

Abstract read
In one paragraph

Article in Chemical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anne SchuhmacherLaboratory of Organic Chemistry, Eidgenössische Technische Hochschule (ETH) Zurich Vladimir-Prelog-Weg 3 8093 Zurich Switzerland bode@org.chem.ethz.ch.
Tomoya ShiroLaboratory of Organic Chemistry, Eidgenössische Technische Hochschule (ETH) Zurich Vladimir-Prelog-Weg 3 8093 Zurich Switzerland bode@org.chem.ethz.ch.
Sarah J RyanSmall Molecule Design and Development, Eli Lilly and Company Indianapolis IN 46285 USA.
Jeffrey W BodeLaboratory of Organic Chemistry, Eidgenössische Technische Hochschule (ETH) Zurich Vladimir-Prelog-Weg 3 8093 Zurich Switzerland bode@org.chem.ethz.ch.ORCID https://orcid.org/0000-0001-8394-8910

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although highly effective for most amide syntheses, the activation of carboxylic acids requires the use of problematic coupling reagents and is often poorly suited for challenging cases such as

Identifiers

PMID34094137
PMCPMC8152719

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.