Evidence map›Paper›PMID 34094012›Full record

ArticleClinics in orthopedic surgery2021

Does Demineralized Bone Matrix Enhance Tendon-to-Bone Healing after Rotator Cuff Repair in a Rabbit Model?

Woo-Yong Lee, Young-Mo Kim, Deuk-Soo Hwang, Hyun-Dae Shin, Yong-Bum Joo, Soo-Min Cha, Kyung-Hee Kim, Yoo-Sun Jeon, Sun-Yeul Lee

Abstract readComparative Study
In one paragraph

Article in Clinics in orthopedic surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Woo-Yong LeeDepartment of Orthopedic Surgery, Regional Rheumatoid and Degenerative Arthritis Center, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Korea.ORCID https://orcid.org/0000-0001-8706-6026
Young-Mo KimDepartment of Orthopedic Surgery, Regional Rheumatoid and Degenerative Arthritis Center, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Korea.ORCID https://orcid.org/0000-0002-6969-4499
Deuk-Soo HwangDepartment of Orthopedic Surgery, Regional Rheumatoid and Degenerative Arthritis Center, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Korea.ORCID https://orcid.org/0000-0003-1009-3784
Hyun-Dae ShinDepartment of Orthopedic Surgery, Regional Rheumatoid and Degenerative Arthritis Center, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Korea.ORCID https://orcid.org/0000-0003-4290-1125
Yong-Bum JooDepartment of Orthopedic Surgery, Regional Rheumatoid and Degenerative Arthritis Center, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Korea.ORCID https://orcid.org/0000-0003-4130-7431
Soo-Min ChaDepartment of Orthopedic Surgery, Regional Rheumatoid and Degenerative Arthritis Center, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Korea.ORCID https://orcid.org/0000-0003-1663-406X
Kyung-Hee KimDepartment of Pathology, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Korea.ORCID https://orcid.org/0000-0003-0214-0296
Yoo-Sun JeonDepartment of Orthopedic Surgery, Regional Rheumatoid and Degenerative Arthritis Center, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Korea.ORCID https://orcid.org/0000-0003-4391-0349
Sun-Yeul LeeDepartment of Anesthesiology and Pain Medicine, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Korea.ORCID https://orcid.org/0000-0002-6124-5138

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroudThe purpose of this study was to compare the histologic outcomes of rotator cuff (RC) repair with demineralized bone matrix (DBM) augmentation and those without DBM augmentation and to evaluate the role of DBM for tendon-to-bone (TB) healing in a rabbit model.

methodsTwenty-six adult male New Zealand white rabbits were randomly allocated to the control group (n = 13) or the DBM group (n = 13). Repair was performed 8 weeks after complete transection of the right supraspinatus tendon of all rabbits. In the control group, RC repair was achieved by a standard transosseous technique. In the DBM group, RC repair was achieved using the same technique, and DBM was interposed between the cuff and bone. After 8 weeks, the RC tendon entheses from all rabbits were processed for gross and histologic examination.

resultsOn gross TB healing, 2 of 11 specimens in the control group were unhealed and no specimen was grossly unhealed in the DBM group (

conclusionsThe use of DBM for TB interface healing in rabbit experiments showed good results in gross and histologic analysis. However, it is difficult to draw a solid conclusion because the sample size is small. Further evaluation in the

Indexed as

Bone MatrixWound HealingAnimalsDisease Models, AnimalMaleRabbitsRotator Cuff InjuriesTendon InjuriesDemineralized bone matrixRepairRotator cuffTearTendon-to-bone healing

Identifiers

PMID34094012
PMCPMC8173240

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.