Evidence map›Paper›PMID 34093893›Full record

ArticleNuclear medicine and molecular imaging2021

The Outcome and Safety of Re-challenge Lutetium-177 PSMA (

Masha Maharaj, Lucille Heslop, Trisha Govender, Nisaar Korowlay, Aviral Singh, Partha Choudhary, Mike Sathekge

Open access · greenAbstract readCase Reports
In one paragraph

Article in Nuclear medicine and molecular imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Framework to calculateMedical physics · 2025
    Article
  3. Radionuclides Landscape in Prostate Cancer Theranostics.International journal of molecular sciences · 2025
    Review
  4. Review
  5. Article
  6. Article
  7. Efficacy and safety of rechallenge [European journal of nuclear medicine and molecular imaging · 2024
    Observational
  8. Review
  9. Article
  10. Review
  11. Biomedicines · 2021
    Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Masha MaharajDepartment of Nuclear Medicine, Imaging and Therapy Centres of Excellence, Durban, KwaZulu Natal South Africa.ORCID 0000-0003-4934-0172
Lucille HeslopDurban Oncology Centre, West Ridge, Durban, South Africa.
Trisha GovenderDepartment of Nuclear Medicine, Imaging and Therapy Centres of Excellence, Durban, KwaZulu Natal South Africa.
Nisaar KorowlayDivision of Nuclear Medicine, Tygerberg Hospital, Stellenbosch University, Stellenbosch, South Africa.
Aviral SinghTheranostics Center for Molecular Radiotherapy and Molecular Imaging (PET/CT) ENETS Center of Excellence, Zentralklinik Bad Berka GmbH, Bad Berka, Germany.
Partha ChoudharyDepartment of Nuclear Medicine, Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, India.
Mike SathekgeDepartment of Nuclear Medicine, University of Pretoria & Steve Biko Academic Hospital, Pretoria, South Africa.
University of KwaZulu-Natal · ZARajiv Gandhi Cancer Institute and Research Centre · INStellenbosch University · ZASteve Biko Hospital · ZAZentralklinik Bad Berka · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate-specific membrane antigen (PSMA)-directed radioligand therapy (PSMA-RLT) with lutetium-177 (

Indexed as

177LuDocetaxelProstate cancerPSMARadiosensitizerRe-challenge

Identifiers

PMID34093893
PMCPMC8139998
OpenAlexW3154599308

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.