Evidence map›Paper›PMID 34093857›Full record

ArticleTheranostics2021

Cancer-derived exosomal miR-138-5p modulates polarization of tumor-associated macrophages through inhibition of KDM6B.

Jing Xun, Lingfang Du, Ruifang Gao, Long Shen, Dekun Wang, Lichun Kang, Chuan'ai Chen, Zhujun Zhang, Yuying Zhang, Shijing Yue and 4 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 110 papers.

0numbers the graph read from it
0cells of the map it votes in
110citing papers in PubMed
8.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

110 citing papers in PubMed, 151 citations in OpenAlex.

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  12. Immunity and Beyond: Emerging Roles of Monocytes and Macrophages in Cancer.Advances in experimental medicine and biology · 2026
    Review
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50 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Jing XunSchool of Medicine, Nankai University, Tianjin 300071, China.
Lingfang DuSchool of Medicine, Nankai University, Tianjin 300071, China.
Ruifang GaoSchool of Medicine, Nankai University, Tianjin 300071, China.
Long ShenSchool of Medicine, Nankai University, Tianjin 300071, China.
Dekun WangSchool of Medicine, Nankai University, Tianjin 300071, China.
Lichun KangSchool of Medicine, Nankai University, Tianjin 300071, China.
Chuan'ai ChenSchool of Medicine, Nankai University, Tianjin 300071, China.
Zhujun ZhangSchool of Medicine, Nankai University, Tianjin 300071, China.
Yuying ZhangSchool of Medicine, Nankai University, Tianjin 300071, China.
Shijing YueSchool of Medicine, Nankai University, Tianjin 300071, China.
Shuxin FengDepartment of Orthopedics, Tianjin First Central Hospital, Tianjin, 300071, China.
Rong XiangSchool of Medicine, Nankai University, Tianjin 300071, China.
Xue MiSchool of Medicine, Nankai University, Tianjin 300071, China.
Xiaoyue TanSchool of Medicine, Nankai University, Tianjin 300071, China.
Nankai University · CNTianjin Nankai Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsBreast NeoplasmsCell Line, TumorChromatin ImmunoprecipitationCoculture TechniquesDown-RegulationExosomesFemaleGene Expression Regulation, NeoplasticHumansJumonji Domain-Containing Histone DemethylasesLung NeoplasmsMiceMice, Inbred BALB CMicroRNAsNeoplasm MetastasisJumonji Domain-Containing Histone DemethylasesKDM6B protein, humanKdm6b protein, mouseMicroRNAsMIRN138 microRNA, humanexosomeslysine demethylase 6B (KDM6B)macrophage polarizationmicroRNA-138-5ptumor-associated macrophages

Identifiers

PMID34093857
PMCPMC8171095
OpenAlexW3158168797

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.