Evidence map›Paper›PMID 34093789›Full record

ArticleJournal of Cancer2021

YTHDF2 inhibit the tumorigenicity of endometrial cancer via downregulating the expression of IRS1 methylated with m

Ling Hong, Xiaowen Pu, Haili Gan, Lichun Weng, Qingliang Zheng

Open access · goldAbstract read
In one paragraph

Article in Journal of Cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Emerging Roles of mFrontiers in oncology · 2022
    Pooled it
  2. Review
  3. m6A modification and its clinical applications in gynaecological cancer.Apoptosis : an international journal on programmed cell death · 2026
    Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Role of the RNA-binding protein family in gynecologic cancers.American journal of cancer research · 2023
    Review
  10. Review
  11. Article
  12. Roles of NExperimental hematology & oncology · 2022
    Review
  13. Novel insights into roles of N6-methyladenosine reader YTHDF2 in cancer progression.Journal of cancer research and clinical oncology · 2022
    Review
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ling HongShanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai 201204, China.
Xiaowen PuShanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai 201204, China.
Haili GanShanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai 201204, China.
Lichun WengShanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai 201204, China.
Qingliang ZhengShanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai 201204, China.
Shanghai First Maternity and Infant Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

RNA epigenetic modification take part in many biology processes, and the N6-methyladenosine (m

Indexed as

AKT signaling pathwayendometrial cancerIRS1m6A modificationYTHDF2

Identifiers

PMID34093789
PMCPMC8176259
OpenAlexW3158481558

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.