Evidence map›Paper›PMID 34093472›Full record

ArticleFrontiers in microbiology2021

Understanding How Staphylococcal Autolysin Domains Interact With Polystyrene Surfaces.

Radha P Somarathne, Emily R Chappell, Y Randika Perera, Rahul Yadav, Joo Youn Park, Nicholas C Fitzkee

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Radha P SomarathneDepartment of Chemistry, Mississippi State University, Mississippi State, MS, United States.
Emily R ChappellDepartment of Chemistry, Mississippi State University, Mississippi State, MS, United States.
Y Randika PereraDepartment of Biochemistry, Chemistry, and Center for Structural Biology, Vanderbilt University, Nashville, TN, United States.
Rahul YadavDepartment of Chemistry, Mississippi State University, Mississippi State, MS, United States.
Joo Youn ParkDepartment of Comparative Biomedical Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS, United States.
Nicholas C FitzkeeDepartment of Chemistry, Mississippi State University, Mississippi State, MS, United States.
Mississippi State University · USVanderbilt University · US

Funding

Zinc dependent conformational changes in AdcR and their impact on DNA bindingP20GM103646 · NIGMS · MISSISSIPPI STATE UNIVERSITY · PI THIBAUDEAU, GISELLE · 2013 to 2022
$21.1M
Structure, Orientation, and Competitive Interactions of S. Epidermidis Biofilm Proteins on SurfacesR01AI139479 · NIAID · MISSISSIPPI STATE UNIVERSITY · PI FITZKEE, NICHOLAS C · 2018 to 2022
$1.8M
NIAID NIH HHS R01 AI139479NIGMS NIH HHS P20 GM103646
6 · The paper itself

Abstract

Biofilms, when formed on medical devices, can cause malfunctions and reduce the efficiency of these devices, thus complicating treatments and serving as a source of infection. The autolysin protein of

Indexed as

autolysin proteinsbiofilmsmedical implantspolystyrene nanoparticlessurface chemistry

Identifiers

PMID34093472
PMCPMC8170090
OpenAlexW3163836519

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.