Evidence map›Paper›PMID 34093276›Full record

ArticleFrontiers in psychiatry2021

Prefrontal Functional Connectivity During the Verbal Fluency Task in Patients With Major Depressive Disorder: A Functional Near-Infrared Spectroscopy Study.

Suh-Yeon Dong, JongKwan Choi, Yeonsoo Park, Seung Yeon Baik, Minjee Jung, Yourim Kim, Seung-Hwan Lee

Abstract read
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Article in Frontiers in psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

7 authors.

Suh-Yeon DongDepartment of Information Technology Engineering, Sookmyung Women's University, Seoul, South Korea.
JongKwan ChoiOBELAB, Seoul, South Korea.
Yeonsoo ParkDepartment of Psychology, University of Notre Dame, Dame, RI, United States.
Seung Yeon BaikDepartment of Psychology, Penn State University, State College, PA, United States.
Minjee JungClinical Emotion and Cognition Research Laboratory, Inje University, Goyang, South Korea.
Yourim KimDepartment of Psychology, University of Wisconsin-Milwaukee, Milwaukee, WI, United States.
Seung-Hwan LeeClinical Emotion and Cognition Research Laboratory, Inje University, Goyang, South Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deviations in activation patterns and functional connectivity have been observed in patients with major depressive disorder (MDD) with prefrontal hemodynamics of patients compared with healthy individuals. The graph-theoretical approach provides useful network metrics for evaluating functional connectivity. The evaluation of functional connectivity during a cognitive task can be used to explain the neurocognitive mechanism underlying the cognitive impairments caused by depression. Overall, 31 patients with MDD and 43 healthy individuals completed a verbal fluency task (VFT) while wearing a head-mounted functional near-infrared spectroscopy (fNIRS) devices. Hemodynamics and functional connectivity across eight prefrontal subregions in the two groups were analyzed and compared. We observed a reduction in prefrontal activation and weaker overall and interhemispheric subregion-wise correlations in the patient group compared with corresponding values in the control group. Moreover, efficiency, the network measure related to the effectiveness of information transfer, showed a significant between-group difference [t (71.64) = 3.66, corrected p < 0.001] along with a strong negative correlation with depression severity (rho = -0.30,

Indexed as

efficiencyfNIRSfunctional connectivitymajor depressive disorderverbal fluency task

Identifiers

PMID34093276
PMCPMC8175962

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.