Evidence map›Paper›PMID 34093255›Full record

ArticleFrontiers in psychiatry2021

Urine Nitric Oxide Is Lower in Parents of Autistic Children.

Lulu Yao, Kun Cai, Fanghua Mei, Xiaohua Wang, Chuangang Fan, Hong Jiang, Fang Xie, Ying Li, Lu Bai, Kang Peng and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Lulu YaoNational 111 Center for Cellular Regulation and Molecular Pharmaceutics, Hubei University of Technology, Wuhan, China.
Kun CaiHubei Provincial Center for Disease Control and Prevention, Wuhan, China.
Fanghua MeiHubei Provincial Center for Disease Control and Prevention, Wuhan, China.
Xiaohua WangSchool of Social Development and Public Policy, Beijing Normal University, Beijing, China.
Chuangang FanHubei Provincial Center for Disease Control and Prevention, Wuhan, China.
Hong JiangDepartment of Child Health Care, Huangshi Maternity and Child Health Care Hospital, Wuhan, China.
Fang XieDepartment of Child Health Care, Huangshi Maternity and Child Health Care Hospital, Wuhan, China.
Ying LiDepartment of Child Health Care, Huangshi Maternity and Child Health Care Hospital, Wuhan, China.
Lu BaiNational 111 Center for Cellular Regulation and Molecular Pharmaceutics, Hubei University of Technology, Wuhan, China.
Kang PengNational 111 Center for Cellular Regulation and Molecular Pharmaceutics, Hubei University of Technology, Wuhan, China.
Wenwen DengNational 111 Center for Cellular Regulation and Molecular Pharmaceutics, Hubei University of Technology, Wuhan, China.
Shenghan LaiDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Jun WangNational 111 Center for Cellular Regulation and Molecular Pharmaceutics, Hubei University of Technology, Wuhan, China.
Hubei University of Technology · CNHubei Provincial Center for Disease Control and Prevention · CNLishui Maternity and Child Health Care Hospital · CNBeijing Normal University · CNJohns Hopkins Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parents raising children with autism spectrum disorder (ASD) usually carry on their daily life under tremendous stress, but limited empirical research has been devoted to this population. It is known that parents' health status directly impacts therapeutic outcome of ASD children. As an important regulator in cardiovascular, nervous and immune systems, nitric oxide (NO) levels haven't been reported in parents of ASD children yet. In this study, we measured urine nitrite and nitrate from 43 ASD parents (ASD-P), and 43 healthy adults in the same range of age (Control) who didn't have any ASD descendants. Comparison between the ASD-P and Control groups showed that

Indexed as

autism spectrum disordernitratenitric oxidenitriteparentsurine

Identifiers

PMID34093255
PMCPMC8175662
OpenAlexW3165297694

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.