Evidence map›Paper›PMID 34093197›Full record

ArticleFrontiers in pharmacology2021

Dapsone Ameliorates Isoproterenol-Induced Myocardial Infarction

Walaa Yehia Abdelzaher, Sabreen Mahmoud Ahmed, Nermeen N Welson, Khalaf F Alsharif, Gaber El-Saber Batiha, Dina A Aly Labib

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 54 citations in OpenAlex.

  1. Review
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  5. Exploring the Cardioprotective Potential ofCardiovascular & hematological disorders drug targets · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Walaa Yehia AbdelzaherDepartment of Pharmacology, Faculty of Medicine, Minia University, Minia, Egypt.
Sabreen Mahmoud AhmedDepatment of Human Anatomy and Embryology, Faculty of Medicine, Minia University, Delegated to Deraya University, Minia, Egypt.
Nermeen N WelsonDepartment of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt.
Khalaf F AlsharifDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taif University, Taif, Saudi Arabia.
Gaber El-Saber BatihaDepartment of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour, Egypt.
Dina A Aly LabibDepartment of Pharmacology, Faculty of Medicine, Cairo University, Giza, Egypt.
Minia University · EGBeni-Suef University · EGCairo University · EGDamanhour University · EGTaif University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myocardial infarction (MI) is a critical condition that can happen with high doses or rapid termination of beta blockers therapy. The study aimed to evaluate the potential anti-toxic value of DAP against isoproterenol (ISO) - induced MI. Twenty-eight male Wistar rats were used for the study. The rodents were assigned to four groups (

Indexed as

dapsoneHO-1myocardial infarctionNrf2TLR4

Identifiers

PMID34093197
PMCPMC8170324
OpenAlexW3163600686

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.