Evidence map›Paper›PMID 34093172›Full record

ArticleFrontiers in pharmacology2021

Ochuko L Erukainure, Chika I Chukwuma, Motlalepula G Matsabisa, Mirranda T Javu, Veronica F Salau, Neil A Koorbanally, Md Shahidul Islam

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Cardioprotective Effect ofJournal of pharmacopuncture · 2024
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Ochuko L ErukainureDepartment of Pharmacology, Faculty of Health Sciences, School of Clinical Medicine, University of the Free State, Bloemfontein, South Africa.
Chika I ChukwumaCenter for Quality of Health and Living, Faculty of Health and Environmental Sciences, Central University of Technology, Bloemfontein, South Africa.
Motlalepula G MatsabisaDepartment of Pharmacology, Faculty of Health Sciences, School of Clinical Medicine, University of the Free State, Bloemfontein, South Africa.
Mirranda T JavuDepartment of Pharmacology, Faculty of Health Sciences, School of Clinical Medicine, University of the Free State, Bloemfontein, South Africa.
Veronica F SalauDepartment of Biochemistry, School of Life Sciences, University of KwaZulu-Natal, Durban, South Africa.
Neil A KoorbanallySchool of Chemistry and Physics, University of KwaZulu-Natal, Durban, South Africa.
Md Shahidul IslamDepartment of Biochemistry, School of Life Sciences, University of KwaZulu-Natal, Durban, South Africa.
University of KwaZulu-Natal · ZAUniversity of the Free State · ZACentral University of Technology · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiotoxicity leading to cardiovascular dysfunction and ultimately cardiac failure remains a major global health issue irrespective of race, age and country. Several factors including lipotoxicity, oxidative imbalance, exacerbated angiotensin-converting enzyme (ACE) activity and altered bioenergetics have been implicated in the pathophysiology of cardiovascular diseases.

Indexed as

cardiometabolismcardiotoxicitylipid dysmetabolismmetabolomicsturbina oblongata

Identifiers

PMID34093172
PMCPMC8174711
OpenAlexW3161041430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.