Evidence map›Paper›PMID 34093148›Full record

ReviewFrontiers in behavioral neuroscience2021

Cortical Contributions to Higher-Order Conditioning: A Review of Retrosplenial Cortex Function.

Danielle I Fournier, Han Yin Cheng, Siobhan Robinson, Travis P Todd

Abstract readReview
In one paragraph

Review in Frontiers in behavioral neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Danielle I FournierDepartment of Psychological and Brain Sciences, Dartmouth College, Hanover, NH, United States.
Han Yin ChengDepartment of Psychological and Brain Sciences, Dartmouth College, Hanover, NH, United States.
Siobhan RobinsonProgram in Neuroscience, Psychology Department, Hamilton College, Clinton, NY, United States.
Travis P ToddDepartment of Psychological and Brain Sciences, Dartmouth College, Hanover, NH, United States.

Funding

Training in the Science of Co-Occurring DisordersT32DA037202 · NIDA · DARTMOUTH COLLEGE · PI Lisa A. Marsch · 2014 to 2026
$4.7M
Cortical circuitry and mechanisms underlying remote cue-specific fear memory and extinctionR01MH118734 · NIMH · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI GULLEDGE, ALLAN T, SMITH, KYLE S · 2019 to 2023
$2.4M
Cortical ensemble coding and circuit dynamics of fear suppressionK01MH116158 · NIMH · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI TODD, TRAVIS · 2018 to 2021
$651k
NIDA NIH HHS T32 DA037202NIMH NIH HHS K01 MH116158NIMH NIH HHS R01 MH118734
6 · The paper itself

Abstract

In higher-order conditioning paradigms, such as sensory preconditioning or second-order conditioning, discrete (e.g., phasic) or contextual (e.g., static) stimuli can gain the ability to elicit learned responses despite never being directly paired with reinforcement. The purpose of this mini-review is to examine the neuroanatomical basis of high-order conditioning, by selectively reviewing research that has examined the role of the retrosplenial cortex (RSC) in sensory preconditioning and second-order conditioning. For both forms of higher-order conditioning, we first discuss the types of associations that may occur and then review findings from RSC lesion/inactivation experiments. These experiments demonstrate a role for the RSC in sensory preconditioning, suggesting that this cortical region might contribute to higher-order conditioning via the encoding of neutral stimulus-stimulus associations. In addition, we address knowledge gaps, avenues for future research, and consider the contribution of the RSC to higher-order conditioning in relation to related brain structures.

Indexed as

associative learninghigher-order conditioningretrosplenial cortexsecond-order conditioningsensory preconditioning

Identifiers

PMID34093148
PMCPMC8170078

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.