ArticleJournal of Taibah University Medical Sciences2021
Seroprevalence of COVID-19 and associated factors in a medical institution in Pakistan.
Article in Journal of Taibah University Medical Sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 7 citations in OpenAlex.
- Seroprevalence of SARS-COV-2 Antibodies Associated with the Use of Personal Protective Equipment in Healthcare Workers.Materia socio-medica · 2024Article
- COVID-19: Establishing, implementing and assessment safety strategy, descriptive interventional study.PloS one · 2023Article
- Humoral immune response to COVID-19 infection or vaccination among celiac disease patients.Central-European journal of immunology · 2022Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study investigates the association of preventive measures with coronavirus disease (COVID-19) seropositivity.
methodsThis cross-sectional study was conducted at the Combined Military Hospital Kharian Medical College, Pakistan, in September 2020. A total of 442 participants from three different strata (faculty, students, and administration/technical staff) were enrolled using a convenient sampling technique. A rapid antibody testing method was used to detect antibodies. The Ichroma™ COVID-19 Ab test is an in vitro diagnostic device that helps in the rapid identification of COVID-19 by measuring the levels of IgG and IgM antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the blood. An automated fluorescent immunoassay system (AFIAS-6), with a clinical sensitivity of 95.8% and specificity of 96.7%, was used for qualitative analysis. A self-administered questionnaire was used to collect data, and data analysis was performed using SPSS version 25.
resultsIn total, 442 participants were included in the study: 40 (9%) faculty members, 299 (67%) students, and 103 (23.3%) administrative/technical staff. As many as 14.9% of the participants were symptomatic; 32.4% always used masks, and 14% never wore masks. Furthermore, 69.7% of participants frequently washed their hands for 20 s, and 75.6% were aware of social distancing. A total of 16.96% of participants tested positive for IgG antibodies. Moreover, most of the administration/technical staff who tested positive for IgG were asymptomatic (68.42%). A significant association (
conclusionThis study showed a higher seroprevalence rate than other studies as it was conducted toward the end of the first wave of the COVID-19 pandemic. However, we are still far from achieving herd immunity. Furthermore, strict compliance with preventive measures is the only way to ensure safety until an effective vaccine is developed.
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