Evidence map›Paper›PMID 34092738›Full record

ArticleInternal medicine (Tokyo, Japan)2021

Renal Involvement as Rare Acute Tubulointerstitial Nephritis in a Patient with Eosinophilic Disorder Treated with Early Add-on Administration of Mepolizumab.

Yuto Hayama, Fuminori Tomyo, Masaki Ueno, Shinichiro Asakawa, Shigeyuki Arai, Osamu Yamazaki, Yoshifuru Tamura, Makoto Mochizuki, Ryuji Ohashi, Shigeru Shibata and 1 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Yuto HayamaDepartment of Internal Medicine, Teikyo University School of Medicine, Japan.
Fuminori TomyoDepartment of Internal Medicine, Teikyo University School of Medicine, Japan.
Masaki UenoDepartment of Internal Medicine, Teikyo University School of Medicine, Japan.
Shinichiro AsakawaDepartment of Internal Medicine, Teikyo University School of Medicine, Japan.
Shigeyuki AraiDepartment of Internal Medicine, Teikyo University School of Medicine, Japan.
Osamu YamazakiDepartment of Internal Medicine, Teikyo University School of Medicine, Japan.
Yoshifuru TamuraDepartment of Internal Medicine, Teikyo University School of Medicine, Japan.
Makoto MochizukiDepartment of Clinical Laboratory Science, Faculty of Medical Technology, Teikyo University, Japan.
Ryuji OhashiDepartment of Integrated Diagnostic Pathology, Nippon Medical School, Japan.
Shigeru ShibataDepartment of Internal Medicine, Teikyo University School of Medicine, Japan.
Yoshihide FujigakiDepartment of Internal Medicine, Teikyo University School of Medicine, Japan.
Teikyo University · JPNippon Medical School · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 39-year-old man presented with peripheral eosinophilia, pulmonary eosinophilic infiltrate, and renal failure due to acute tubulointerstitial nephritis (TIN). He had experienced childhood asthma and was negative for anti-neutrophil cytoplasmic antibody (ANCA). He was tentatively diagnosed with ANCA-negative eosinophilic granulomatous polyangiitis (EGPA) or idiopathic hypereosinophilic syndrome (HES). Renal involvement of isolated TIN with eosinophil infiltration is rare in EGPA and HES and does not seem to have a good prognosis in the literature. However, his condition improved well with corticosteroids and mepolizumab. The revised classification of EGPA based on the etiology should dictate the proper treatment in suspected EGPA patients with nonsystemic vasculitis.

Indexed as

Churg-Strauss SyndromeGranulomatosis with PolyangiitisNephritis, InterstitialAdultAntibodies, Monoclonal, HumanizedChildHumansMaleAntibodies, Monoclonal, Humanizedmepolizumabanti-neutrophil cytoplasmic antibodyeosinophilic granulomatosis with polyangiitishypereosinophilic syndromemepolizumabtubulointerstitial nephritis

Identifiers

PMID34092738
PMCPMC8710382
OpenAlexW3166484212

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.