Evidence map›Paper›PMID 34092240›Full record

ArticleRadiation oncology (London, England)2021

Geometric and dosimetric impact of 3D generative adversarial network-based metal artifact reduction algorithm on VMAT and IMPT for the head and neck region.

Mitsuhiro Nakamura, Megumi Nakao, Keiho Imanishi, Hideaki Hirashima, Yusuke Tsuruta

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Article in Radiation oncology (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

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8citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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8 citing papers in PubMed.

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5 · Who and what money

Authors and funding

5 authors.

Mitsuhiro NakamuraDivision of Medical Physics, Department of Information Technology and Medical Engineering, Human Health Sciences, Graduate School of Medicine, Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan. m_nkmr@kuhp.kyoto-u.ac.jp.ORCID http://orcid.org/0000-0001-5007-8808
Megumi NakaoDepartment of Systems Science, Graduate School of Informatics, Kyoto University, Kyoto, Japan.
Keiho Imanishie-Growth Co., Ltd., Hyogo, Japan.
Hideaki HirashimaDepartment of Radiation Oncology and Image-Applied Therapy, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Yusuke TsurutaDivision of Medical Physics, Department of Information Technology and Medical Engineering, Human Health Sciences, Graduate School of Medicine, Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan.

Funding

Japan Agency for Medical Research and Development 21lm0203013j0003Japan Society for the Promotion of Science 18K19918National Cancer Center Research and Development Fund 31-A-17Subsidies for promoting next-generation local industries 2019, Kyoto
6 · The paper itself

Abstract

backgroundWe investigated the geometric and dosimetric impact of three-dimensional (3D) generative adversarial network (GAN)-based metal artifact reduction (MAR) algorithms on volumetric-modulated arc therapy (VMAT) and intensity-modulated proton therapy (IMPT) for the head and neck region, based on artifact-free computed tomography (CT) volumes with dental fillings.

methodsThirteen metal-free CT volumes of the head and neck regions were obtained from The Cancer Imaging Archive. To simulate metal artifacts on CT volumes, we defined 3D regions of the teeth for pseudo-dental fillings from the metal-free CT volumes. HU values of 4000 HU were assigned to the selected teeth region of interest. Two different CT volumes, one with four (m4) and the other with eight (m8) pseudo-dental fillings, were generated for each case. These CT volumes were used as the Reference. CT volumes with metal artifacts were then generated from the Reference CT volumes (Artifacts). On the Artifacts CT volumes, metal artifacts were manually corrected for using the water density override method with a value of 1.0 g/cm

resultsThe time required to generate a single GAN-MAR CT volume was approximately 30 s. The median SSIMs were lower in the m8 group than those in the m4 group, and ANOVA showed a significant difference in the SSIM for the m8 group (p < 0.05). Although the median differences in D

conclusionsThe GAN-MAR CT volumes generated in a short time were closer to the Reference CT volumes than the Water and Artifacts CT volumes. The observed dosimetric differences compared to the reference plan were clinically acceptable.

Indexed as

AlgorithmsArtifactsHeadHead and Neck NeoplasmsHumansMetalsNeckNeural Networks, ComputerRadiometryRadiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-AssistedTomography, X-Ray ComputedMetals3D GANHead and neck cancerMetal artifact reductionVMAT and IMPT

Identifiers

PMID34092240
PMCPMC8182914

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.