Evidence map›Paper›PMID 34092058›Full record

SynthesisHaematologica2021

Chromosome 1q21 abnormalities refine outcome prediction in patients with multiple myeloma - a meta-analysis of 2,596 trial patients.

Niels Weinhold, Hans J Salwender, David A Cairns, Marc S Raab, George Waldron, Igor W Blau, Uta Bertsch, Thomas Hielscher, Gareth J Morgan, Anna Jauch and 8 more

Abstract readLetterMeta-Analysis
In one paragraph

Synthesis in Haematologica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. International Myeloma Society/International Myeloma Working Group Consensus Recommendations on the Definition of High-Risk Multiple Myeloma.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2025
    Guideline
  4. Pooled it
  5. Trial
  6. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Niels WeinholdDepartment of Internal Medicine V, University Clinic Heidelberg, Heidelberg. Niels.Weinhold@med.uni-heidelberg.de.
Hans J SalwenderAsklepios Tumorzentrum Hamburg, AK Altona and AK St. Georg, Hamburg.
David A CairnsClinical Trials Research Unit, Leeds Institute of Clinical Trials Research, Leeds.
Marc S RaabDepartment of Internal Medicine V, University Clinic Heidelberg, Heidelberg.
George WaldronDivision of Genetics and Epidemiology, The Institute of Cancer Research, London.
Igor W BlauMedical Clinic, Charité University Medicine Berlin, Berlin.
Uta BertschDepartment of Internal Medicine V, University Clinic Heidelberg, Heidelberg.
Thomas HielscherDivision of Biostatistics, German Cancer Research Center (DKFZ) Heidelberg, Heidelberg.
Gareth J MorganPerlmutter Cancer Center, NYU Langone Health, New York.
Anna JauchInstitute of Human Genetics, University of Heidelberg, Heidelberg.
Faith E DaviesPerlmutter Cancer Center, NYU Langone Health, New York.
Mathias HänelDepartment of Internal Medicine III, Klinikum Chemnitz, Chemnitz.
Gordon CookLeeds Institute of Cancer and Pathology, University of Leeds, Leeds.
Christoph ScheidDepartment I of Internal Medicine and Center of Integrated Oncology Cologne Bonn, University of Cologne, Cologne.
Richard HoulstonDivision of Genetics and Epidemiology, The Institute of Cancer Research, London.
Hartmut GoldschmidtDepartment of Internal Medicine V, University Clinic Heidelberg, Heidelberg, Germany; National Center for Tumor Diseases (NCT), University Clinic Heidelberg, Heidelberg.
Graham JacksonDepartment of Haematology, University of Newcastle, Newcastle Upon Tyne.
Martin F KaiserDivision of Genetics and Epidemiology, The Institute of Cancer Research, London, United Kingdom; Department of Haematology, The Royal Marsden Hospital, London. martin.kaiser@icr.ac.uk.

Funding

Cancer Research UK 25447Cancer Research UK C1298/A10410
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Multiple MyelomaChromosome AberrationsChromosomesChromosomes, Human, Pair 1HumansPrognosis

Identifiers

PMID34092058
PMCPMC8485656

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.