Evidence map›Paper›PMID 34092054›Full record

GuidelineThe Korean journal of internal medicine2021

Evidence based guidelines for the treatment of Helicobacter pylori infection in Korea 2020.

Hye-Kyung Jung, Seung Joo Kang, Yong Chan Lee, Hyo-Joon Yang, Seon-Young Park, Cheol Min Shin, Sung Eun Kim, Hyun Chul Lim, Jie-Hyun Kim, Su Youn Nam and 6 more

Abstract readPractice Guideline
In one paragraph

Guideline in The Korean journal of internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Use of Mendelian Randomization to Unveil Metabolic Markers inJournal of Korean medical science · 2026
    Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Saucerneol D Suppresses the Growth ofCurrent issues in molecular biology · 2025
    Article
  9. Article
  10. Impact of Helicobacter pylori Screening on Gastric Cancer Incidence and Mortality.The Korean journal of helicobacter and upper gastrointestinal research · 2025
    Article
  11. Antibiotic Resistance of Helicobacter pylori: Current Trends in Daegu-Kyungpook.The Korean journal of helicobacter and upper gastrointestinal research · 2025
    Article
  12. Etiology and Therapeutic Strategies for Refractory Peptic Ulcers: A Comprehensive Review.The Korean journal of helicobacter and upper gastrointestinal research · 2025
    Review
  13. Article
  14. [Current Status and Future Perspectives of Tegoprazan-BasedThe Korean journal of helicobacter and upper gastrointestinal research · 2024
    Article
  15. Types of 23S Ribosomal RNA Point Mutations AffectingThe Korean journal of helicobacter and upper gastrointestinal research · 2023
    Article
  16. OptimizingGut and liver · 2023
    Review
  17. [Vonoprazan-based Dual and Triple Therapy forThe Korean journal of helicobacter and upper gastrointestinal research · 2023
    Article
  18. Efficacy of 7-day Tailored Therapy forThe Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2023
    Article
  19. Development of a New Liquid Type Rapid Urease Test Kit (HelicotestThe Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2023
    Article
  20. Stomach cancer burden in China: Epidemiology and prevention.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Hye-Kyung JungDepartment of Internal Medicine, Ewha Womans University School of Medicine, Seoul, Korea.
Seung Joo KangDepartment of Internal Medicine, Seoul National University Hospital Healthcare System Gangnam Center, Seoul, Korea.
Yong Chan LeeDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Hyo-Joon YangDivision of Gastroenterology, Department of Internal Medicine and Gastrointestinal Cancer Center, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.
Seon-Young ParkDepartment of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea.
Cheol Min ShinDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
Sung Eun KimDepartment of Internal Medicine, Kosin University College of Medicine, Busan, Korea.
Hyun Chul LimDepartment of Internal Medicine, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin, Korea.
Jie-Hyun KimDepartment of Internal Medicine and Institute of Gastroenterology, Yonsei University College of Medicine, Seoul, Korea.
Su Youn NamCenter for Gastric Cancer, Kyungpook National University Chilgok Hospital, Daegu, Korea.
Woon Geon ShinDepartment of Internal Medicine, Hallym University College of Medicine, Chuncheon, Korea.
Jae Myung ParkDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Il Ju ChoiCenter for Gastric Cancer, National Cancer Center, Goyang, Korea.
Jae Gyu KimDepartment of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea.
Miyoung ChoiDivision of Healthcare Technology Assessment Research, National Evidence-based Healthcare Collaborating Agency, Seoul, Korea.
Korean College of Helicobacter and Upper Gastrointesinal Research

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Helicobacter pylori infection is one of the most common infectious diseases worldwide. H. pylori is responsible for substantial gastrointestinal morbidity with a high disease burden. Since the revision of the H. pylori Clinical Practice Guidelines in 2013 in Korea, the eradication rate of H. pylori has gradually decreased with the use of a clarithromycin based triple therapy. According to a nationwide randomized controlled study by the Korean College of Helicobacter and Upper Gastrointestinal Research released in 2018, the intention-to-treat eradication rate was only 63.9%, which was mostly due to increased antimicrobial resistance to clarithromycin. The clinical practice guidelines for treatment of H. pylori were updated based on evidence-based medicine from a meta-analysis conducted on a target group receiving the latest level of eradication therapy. The draft recommendations developed based on the meta-analysis were finalized after expert consensus on three recommendations regarding the indication for treatment and eight recommendations on the treatment itself. These guidelines were designed to provide clinical evidence for the treatment of H. pylori to patients, nurses, medical school students, policymakers, and clinicians. These may differ from current medical insurance standards, and will be revised if more evidence emerges in the future.

Indexed as

Helicobacter InfectionsAmoxicillinAnti-Bacterial AgentsClarithromycinDrug Therapy, CombinationHelicobacter pyloriHumansMeta-Analysis as TopicProton Pump InhibitorsRandomized Controlled Trials as TopicRepublic of KoreaAmoxicillinAnti-Bacterial AgentsClarithromycinProton Pump InhibitorsGuidelinesHelicobacter pyloriMeta-analysisMicrobial sensitivity testsTreatment

Identifiers

PMID34092054
PMCPMC8273819

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.