Evidence map›Paper›PMID 34091888›Full record

ArticleClinical pharmacology and therapeutics2021

Pharmacogene Variation Consortium: A Global Resource and Repository for Pharmacogene Variation.

Andrea Gaedigk, Scott T Casey, Michelle Whirl-Carrillo, Neil A Miller, Teri E Klein

Abstract read
In one paragraph

Article in Clinical pharmacology and therapeutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
95citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

95 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Guideline
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  4. Guideline
  5. Guideline
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Article
  10. Article
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  15. Article
  16. Differential impact of Tafenoquine and Primaquine onAntimicrobial agents and chemotherapy · 2026
    Article
  17. Article
  18. Article
  19. Article
  20. Massively parallel reporter assays forbioRxiv : the preprint server for biology · 2026
    Article

35 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Andrea GaedigkDivision of Clinical Pharmacology, Toxicology & Therapeutic Innovation, Children's Mercy Kansas City, Kansas City, Missouri, USA.
Scott T CaseyCenter for Pediatric Genomic Medicine, Children's Mercy Kansas City, Kansas City, Missouri, USA.
Michelle Whirl-CarrilloDepartment of Biomedical Data Science, Stanford University, Stanford, California, USA.
Neil A MillerCenter for Pediatric Genomic Medicine, Children's Mercy Kansas City, Kansas City, Missouri, USA.
Teri E KleinDepartment of Biomedical Data Science, Stanford University, Stanford, California, USA.

Funding

PharmGKB: pharmacogenomics discovery and implementationU24HG010615 · NHGRI · STANFORD UNIVERSITY · PI TERI Ellen KLEIN, Michelle Whirl-Carrillo · 2020 to 2026
$9.5M
PHARMacogene VARiation ConsortiumR24GM123930 · NIGMS · CHILDREN'S MERCY HOSP (KANSAS CITY, MO) · PI GAEDIGK, ANDREA · 2017 to 2020
$1.9M
NHGRI NIH HHS U24 HG010615NIGMS NIH HHS R24 GM123930
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Genetic VariationHumansInactivation, MetabolicPharmacogeneticsReference Standards

Identifiers

PMID34091888
PMCPMC8725060

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.