Evidence map›Paper›PMID 34091867›Full record

ReviewAdvances in therapy2021

Cariprazine, A Broad-Spectrum Antipsychotic for the Treatment of Schizophrenia: Pharmacology, Efficacy, and Safety.

István Laszlovszky, Ágota Barabássy, György Németh

Abstract readReview
In one paragraph

Review in Advances in therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
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  7. Article
  8. Article
  9. ESG-1-60 and ESG-1-61: Novel dopamine DBritish journal of pharmacology · 2025
    Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. D3 Receptor-Targeted Cariprazine: Insights from Lab to Bedside.International journal of molecular sciences · 2024
    Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

István LaszlovszkyMedical Division, Gedeon Richter Plc., Gyömrői út 19-21, 1103, Budapest, Hungary. i.laszlovszky@richter.hu.
Ágota BarabássyMedical Division, Gedeon Richter Plc., Gyömrői út 19-21, 1103, Budapest, Hungary.
György NémethMedical Division, Gedeon Richter Plc., Gyömrői út 19-21, 1103, Budapest, Hungary.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Schizophrenia is characterized by positive, negative, cognitive, and affective symptoms. Antipsychotic medications, which work by blocking the dopamine D

Indexed as

Antipsychotic AgentsSchizophreniaAdultHumansPiperazinesProspective StudiesRandomized Controlled Trials as TopicTreatment OutcomeAntipsychotic AgentscariprazinePiperazinesAtypical antipsychoticCariprazineDopamine D2 receptorDopamine D3 receptorFunctional improvementPartial agonistPredominant negative symptomsSchizophrenia

Identifiers

PMID34091867
PMCPMC8279990

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.