Evidence map›Paper›PMID 34091821›Full record

ArticleClinical journal of gastroenterology2021

A resected case of focal autoimmune pancreatitis with pancreatic duct wall thickening representing periductal lymphoplasmacytic infiltrate.

Keita Ishii, Takeshi Hisa, Akiharu Kudo, Shozo Osera, Tomoaki Shinohara, Akihisa Tomori, Hideki Fukushima

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Clinical journal of gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 89% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Keita IshiiDepartment of Gastroenterology, Saku Central Hospital Advanced Care Center, #106 Monteseresso 3671-46, Nakagomi, Saku-shi, Nagano, 385-0051, Japan. asanoxamd0141@outlook.jp.ORCID http://orcid.org/0000-0001-7872-4226
Takeshi HisaDepartment of Gastroenterology, Saku Central Hospital Advanced Care Center, #106 Monteseresso 3671-46, Nakagomi, Saku-shi, Nagano, 385-0051, Japan.
Akiharu KudoDepartment of Gastroenterology, Saku Central Hospital Advanced Care Center, #106 Monteseresso 3671-46, Nakagomi, Saku-shi, Nagano, 385-0051, Japan.
Shozo OseraDepartment of Gastroenterology, Saku Central Hospital Advanced Care Center, #106 Monteseresso 3671-46, Nakagomi, Saku-shi, Nagano, 385-0051, Japan.
Tomoaki ShinoharaDepartment of Gastroenterology, Saku Central Hospital Advanced Care Center, #106 Monteseresso 3671-46, Nakagomi, Saku-shi, Nagano, 385-0051, Japan.
Akihisa TomoriDepartment of Gastroenterology, Saku Central Hospital Advanced Care Center, #106 Monteseresso 3671-46, Nakagomi, Saku-shi, Nagano, 385-0051, Japan.
Hideki FukushimaDepartment of Gastroenterology, Saku Central Hospital Advanced Care Center, #106 Monteseresso 3671-46, Nakagomi, Saku-shi, Nagano, 385-0051, Japan.
Saku Central Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This case revealed that branch pancreatic duct wall thickening by endoscopic ultrasonography represented periductal lymphoplasmacytic infiltrate as a characteristic histopathological finding of autoimmune pancreatitis, which may help in the diagnosis of autoimmune pancreatitis. An 80-year-old man was referred because fluorodeoxyglucose-positron emission tomography for lung cancer indicated abnormal uptake in the pancreatic head. Computed tomography showed an enhanced mass with cystic structures in the pancreatic head. Magnetic resonance cholangiopancreatography revealed mild dilatation of the main pancreatic duct in the pancreatic body with no strictures. Endoscopic ultrasonography demonstrated a lobulated heterogeneous hypoechoic mass in the pancreatic head. A branch pancreatic duct with wall thickening connected the mass to the main pancreatic duct. An intraductal neoplasm filling and spreading into the branch pancreatic duct was considered, and surgery was performed. Histopathologically, the mass consisted of marked inflammatory cell infiltration, storiform fibrosis, and obliterative phlebitis. The branch pancreatic duct with wall thickening revealed a band-like inflammatory cell infiltration with mainly lymphocytes and plasma cells beneath the normal pancreatic duct epithelium. Immunohistological staining revealed abundant IgG4-positive plasma cells (> 10 cells/HPF) in the inflammatory cell infiltration. The definite diagnosis was type 1 focal autoimmune pancreatitis.

Indexed as

Autoimmune DiseasesAutoimmune PancreatitisPancreatitisAged, 80 and overHumansMalePancreasPancreatic DuctsAutoimmune pancreatitisEndoscopic ultrasonographyIgG4-related diseasePancreatic duct wall thickeningPeriductal lymphoplasmacytic infiltrate

Identifiers

PMID34091821
OpenAlexW3166098281

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.