Evidence map›Paper›PMID 34091749›Full record

ArticlePediatric surgery international2021

Clinical regression of inguinal hernias in premature infants without surgical repair.

Mark A Fleming, David F Grabski, Emmanuel L Abebrese, Daniel E Levin, Sara K Rasmussen, Eugene D McGahren, Jeffrey W Gander

Abstract read
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In one paragraph

Article in Pediatric surgery international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mark A FlemingDepartment of Surgery, University of Virginia School of Medicine, 1215 Lee St, Charlottesville, VA, 22908, USA. MAF2DE@hscmail.mcc.virginia.edu.ORCID https://orcid.org/0000-0001-8589-2439
David F GrabskiDepartment of Surgery, University of Virginia School of Medicine, 1215 Lee St, Charlottesville, VA, 22908, USA.
Emmanuel L AbebreseUniversity of Virginia School of Medicine, Charlottesville, VA, USA.
Daniel E LevinDepartment of Surgery, Division of Pediatric Surgery, University of Virginia School of Medicine, Charlottesville, VA, USA.
Sara K RasmussenDepartment of Surgery, Division of Pediatric Surgery, University of Virginia School of Medicine, Charlottesville, VA, USA.
Eugene D McGahrenDepartment of Surgery, Division of Pediatric Surgery, University of Virginia School of Medicine, Charlottesville, VA, USA.
Jeffrey W GanderDepartment of Surgery, Division of Pediatric Surgery, University of Virginia School of Medicine, Charlottesville, VA, USA.

Funding

NIH HHS 5T32HL007849-20
6 · The paper itself

Abstract

backgroundThe incidence of inguinal hernias in premature infants is approximately 30%. Due to concerns about a high risk of incarceration, early repair is commonly performed. We present a series of patients whose families opted to delay repair until after 55 weeks corrected gestational age (GA) and experienced safe clinical regression of their hernias.

methodsBetween June 2015 and July 2020, premature infants (< 37 weeks GA) diagnosed with inguinal hernias on physical examination were identified. Families of eligible infants were offered either immediate or delayed repair after 55 weeks corrected GA. Infants whose families elected to delay were followed until their hernia(s) clinically regressed, or until older than 55 weeks.

resultsFamilies of 68 infants consented to delay repair. 23 infants (33.8%) had hernias that clinically regressed at median follow up from diagnosis of 14.1 weeks. Univariate analysis demonstrated female sex as a significant predictor of hernia clinical regression (OR: 3.08; p = 0.046). Of the 45 infants who underwent repair, 84.4% safely progressed to 55 weeks corrected GA prior to.

conclusionDelaying inguinal hernia repair in this series of premature infants until after 55 weeks corrected GA revealed that one third of hernias, especially in females, safely regressed upon follow-up examination.

Indexed as

Hernia, InguinalInfant, Premature, DiseasesFemaleHerniorrhaphyHumansInfantInfant, NewbornInfant, PrematureHerniaInguinal herniaInguinal hernia repairPediatric surgeryPremature infants

Identifiers

PMID34091749

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.